4CYF
The structure of vanin-1: defining the link between metabolic disease, oxidative stress and inflammation
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | PANTETHEINASE | polymer | 506 | 56341.2 | 2 | UniProt (O95497) Pfam (PF00795) Pfam (PF19018) | HOMO SAPIENS (HUMAN) | PANTETHEINE HYDROLASE, TIFF66, VASCULAR NON-INFLAMMATORY MOLECULE 1, VANIN-1, HUMAN VANIN-1 |
| 2 | C (C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 1 | In PDB GlyTouCan (G42666HT) | |||
| 3 | D, E, F, G, H... (A, B) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 6 | Chemie (NAG) | |||
| 4 | J, K (A, B) | water | water | 18.0 | 240 | Chemie (HOH) |
Sequence modifications
A, B: 22 - 513 (UniProt: O95497)
| PDB | External Database | Details |
|---|---|---|
| Ala 8 | - | expression tag |
| Ser 9 | - | expression tag |
| Ile 10 | - | expression tag |
| Ser 11 | - | expression tag |
| Ala 12 | - | expression tag |
| Arg 13 | - | expression tag |
| Asp 14 | - | expression tag |
| Tyr 15 | - | expression tag |
| Lys 16 | - | expression tag |
| Asp 17 | - | expression tag |
| Asp 18 | - | expression tag |
| Asp 19 | - | expression tag |
| Asp 20 | - | expression tag |
| Lys 21 | - | expression tag |
| Ile 26 | Thr 26 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 112682.4 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 424.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1327.2 | |
| All* | Total formula weight | 114434.1 |
