4CX7
Structure of human iNOS heme domain in complex with (R)-6-(3-AMINO-2-(5-(2-(6-AMINO-4- METHYLPYRIDIN-2-YL)ETHYL)PYRIDIN-3-YL)PROPYL)-4- METHYLPYRIDIN-2-AMINE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | NITRIC OXIDE SYNTHASE, INDUCIBLE | polymer | 431 | 49705.5 | 4 | UniProt (P35228) Pfam (PF02898) | HOMO SAPIENS (HUMAN) | HEPATOCYTE NOS, HEP-NOS, INDUCIBLE NO SYNTHASE, INDUCIBLE NOS, INOS, NOS TYPE II, PEPTIDYL-CYSTEINE S-NITROSYLASE NOS2, INDUCIBLE NITRIC OXIDE SYNTHASE |
| 2 | E, L, R, X (A, B, C, D) | PROTOPORPHYRIN IX CONTAINING FE | non-polymer | 616.5 | 4 | Chemie (HEM) | |||
| 3 | F, M, S, Y (A, B, C, D) | 5,6,7,8-TETRAHYDROBIOPTERIN | non-polymer | 241.2 | 4 | Chemie (H4B) | |||
| 4 | G, N, T, Z (A, B, C, D) | (R)-6-(3-amino-2-(5-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-3-yl)propyl)-4-methylpyridin-2-amine | non-polymer | 376.5 | 4 | Chemie (S71) | |||
| 5 | AA, H, O, U (D, A, B, C) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | BA, CA, I, J, K... (D, A, B, C) | SULFATE ION | non-polymer | 96.1 | 9 | Chemie (SO4) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 198822.1 | |
| Non-Polymers* | Number of molecules | 25 |
| Total formula weight | 6169.9 | |
| All* | Total formula weight | 204992.0 |
