4CTO
Glucopyranosylidene-spiro-iminothiazolidinone, a New Bicyclic Ring System: Synthesis, Derivatization, and Evaluation as Glycogen Phosphorylase Inhibitors by Enzyme Kinetic and Crystallographic Methods
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | GLYCOGEN PHOSPHORYLASE, MUSCLE FORM | polymer | 843 | 97422.4 | 1 | UniProt (P00489) Pfam (PF00343) | ORYCTOLAGUS CUNICULUS (RABBIT) | MYOPHOSPHORYLASE |
| 2 | B (A) | N-[(2Z,5R,7R,8S,9S,10R)-8,9,10-trihydroxy-7-(hydroxymethyl)-4-oxo-6-oxa-1-thia-3-azaspiro[4.5]dec-2-ylidene]benzamide | non-polymer | 368.4 | 1 | Chemie (M7C) | |||
| 3 | C (A) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
| 4 | D (A) | PHOSPHATE ION | non-polymer | 95.0 | 1 | Chemie (PO4) | |||
| 5 | E (A) | water | water | 18.0 | 287 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 97422.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 710.5 | |
| All* | Total formula weight | 98132.9 |
