4CRP
Solution structure of a TrkAIg2 domain construct for use in drug discovery
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | HIGH AFFINITY NERVE GROWTH FACTOR RECEPTOR | polymer | 107 | 11792.1 | 1 | UniProt (P04629) In PDB | HOMO SAPIENS (HUMAN) | NEUROTROPHIC TYROSINE KINASE RECEPTOR TYPE 1, TRK1-TRANSFORMING TYROSINE KINASE PROTEIN, TROPOMYOSIN-RELATED KINASE A, TYROSINE KINASE RECEPTOR, TYROSINE KINASE RECEPTOR A, TRK-A, GP140TRK, P140-TRKA |
Sequence modifications
A: 6 - 107 (UniProt: P04629)
| PDB | External Database | Details |
|---|---|---|
| Asp 1 | - | expression tag |
| Asp 2 | - | expression tag |
| Asp 4 | - | expression tag |
| Asp 5 | - | expression tag |
| Cys 9 | Pro 285 | engineered mutation |
| Cys 91 | Phe 367 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 11792.1 | |
| All* | Total formula weight | 11792.1 |
