4CPK
Crystal structure of PBP2a double clinical mutant N146K-E150K from MRSA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Penicillin binding protein 2 prime | polymer | 643 | 73431.0 | 2 | UniProt (A0A0H3JPA5) Pfam (PF05223) Pfam (PF03717) Pfam (PF00905) | Staphylococcus aureus (strain Mu50 / ATCC 700699) | |
| 2 | C, D, E, F, G... (A, B) | CADMIUM ION | non-polymer | 112.4 | 11 | Chemie (CD) | |||
| 3 | J, K, Q, R (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 4 | L, S (A, B) | beta-muramic acid | non-polymer | 251.2 | 2 | Chemie (MUR) | |||
| 5 | T, U (A, B) | water | water | 18.0 | 764 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 668 (UniProt: A0A0H3JPA5)
| PDB | External Database | Details |
|---|---|---|
| Lys 146 | Asn 146 | engineered mutation |
| Lys 150 | Glu 150 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 146862.0 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1880.8 | |
| All* | Total formula weight | 148742.8 |
