4CPK
Crystal structure of PBP2a double clinical mutant N146K-E150K from MRSA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Penicillin binding protein 2 prime | polymer | 643 | 73431.0 | 2 | UniProt (A0A0H3JPA5) | Staphylococcus aureus (strain Mu50 / ATCC 700699) | |
| 2 | C, D, E, F, G... (A, B) | CADMIUM ION | non-polymer | 112.4 | 11 | Chemie (CD) PubChem (31193) | |||
| 3 | J, K, Q, R (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) PubChem (312) | |||
| 4 | L, S (A, B) | beta-muramic acid | non-polymer | 251.2 | 2 | Chemie (MUR) PubChem (16219635) PubChem (22833605) PubChem (40488267) PubChem (45039974) PubChem (46782404) PubChem (92146549) PubChem (9816401) PubChem (124922341) PubChem (92274510) PubChem (92274511) PubChem (92274512) PubChem (92274513) PubChem (433580) PubChem (441038) PubChem (446972) PubChem (124922340) PubChem (124922342) PubChem (6452113) PubChem (7058068) PubChem (126968561) PubChem (129696424) PubChem (12313001) PubChem (140369008) PubChem (141806625) PubChem (141808570) PubChem (156619036) PubChem (176059267) | |||
| 5 | T, U (A, B) | water | water | 18.0 | 764 | Chemie (HOH) |
Sequence modifications
A, B: 26 - 668 (UniProt: A0A0H3JPA5)
| PDB | External Database | Details |
|---|---|---|
| Lys 146 | Asn 146 | engineered mutation |
| Lys 150 | Glu 150 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 146862.0 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1880.8 | |
| All* | Total formula weight | 148742.8 |
