4CNV
Surface residue engineering of bovine carbonic anhydrase to an extreme halophilic enzyme for potential application in postcombustion CO2 capture
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | CARBONIC ANHYDRASE 2 | polymer | 262 | 29316.7 | 1 | UniProt (P00921) Pfam (PF00194) | BOS TAURUS (CATTLE) | CARBONATE DEHYDRATASE II, CARBONIC ANHYDRASE II, CA-II |
| 2 | B (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 3 | C, D (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 4 | E (A) | water | water | 18.0 | 249 | Chemie (HOH) |
Sequence modifications
A: 1 - 260 (UniProt: P00921)
| PDB | External Database | Details |
|---|---|---|
| Met -1 | - | expression tag |
| Gly 0 | - | expression tag |
| Asp 24 | Asn 24 | engineered mutation |
| Asp 39 | Val 39 | engineered mutation |
| Asp 57 | Arg 57 | engineered mutation |
| Glu 74 | Gln 74 | engineered mutation |
| Glu 169 | Lys 169 | engineered mutation |
| Asp 252 | Asn 252 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 29316.7 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 249.6 | |
| All* | Total formula weight | 29566.3 |
