4CNI
Crystal structure of the Fab portion of Olokizumab in complex with IL- 6
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, E (A, H) | OLOKIZUMAB HEAVY CHAIN, FAB PORTION | polymer | 220 | 23940.6 | 2 | HOMO SAPIENS (HUMAN) | ||
| 2 | B, F (B, L) | OLOKIZUMAB LIGHT CHAIN, FAB PORTION | polymer | 214 | 23280.8 | 2 | HOMO SAPIENS (HUMAN) | ||
| 3 | C, D (C, D) | INTERLEUKIN-6 | polymer | 171 | 19670.5 | 2 | UniProt (P05231) Pfam (PF00489) | HOMO SAPIENS (HUMAN) | IL-6, B-CELL STIMULATORY FACTOR 2, BSF-2, CTL DIFFERENTIATION FACTOR, CDF, HYBRIDOMA GROWTH FACTOR, INTERFERON BETA-2, IFN-BETA-2 |
| 4 | G, L (A, H) | TRIS(HYDROXYETHYL)AMINOMETHANE | non-polymer | 163.2 | 2 | Chemie (TAM) | |||
| 5 | H, I, J, K, M (C, D, H) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 6 | N, O, P, Q, R... (A, B, C, D, H...) | water | water | 18.0 | 1587 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 133783.7 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 806.7 | |
| All* | Total formula weight | 134590.5 |
