4CN7
Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to an idealized DR1 Response Element
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, E, F (A, B, E, F) | RETINOIC ACID RECEPTOR RXR-ALPHA | polymer | 87 | 10262.9 | 4 | UniProt (P19793) Pfam (PF00105) | HOMO SAPIENS (HUMAN) | NUCLEAR RECEPTOR SUBFAMILY 2 GROUP B MEMBER 1, RETINOID X RECEPTOR ALPHA |
| 2 | C, G (C, G) | 5'-D(*CP*TP*AP*GP*GP*TP*CP*AP*AP*AP*GP*GP*TP*CP *AP*GP)-3' | polymer | 16 | 4947.2 | 2 | HOMO SAPIENS | ||
| 3 | D, H (D, H) | 5'-D(*CP*TP*GP*AP*CP*CP*TP*TP*TP*GP*AP*CP*CP*TP *AP*GP)-3' | polymer | 16 | 4849.2 | 2 | HOMO SAPIENS | ||
| 4 | I, J, M, N, P... (A, B, E, F) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 5 | K, L, O (A, B) | CHLORIDE ION | non-polymer | 35.5 | 3 | Chemie (CL) | |||
| 6 | AA, T, U, V, W... (H, A, B, C, D...) | water | water | 18.0 | 151 | Chemie (HOH) |
Sequence modifications
A, B, E, F: 130 - 212 (UniProt: P19793)
| PDB | External Database | Details |
|---|---|---|
| Gly 126 | - | expression tag |
| Ser 127 | - | expression tag |
| His 128 | - | expression tag |
| Met 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 60644.5 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 629.6 | |
| All* | Total formula weight | 61274.1 |
