4CN5
Crystal Structure of the Human Retinoid X Receptor DNA-Binding Domain Bound to the Human Nr1d1 Response Element
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | RETINOIC ACID RECEPTOR RXR-ALPHA | polymer | 87 | 10262.9 | 2 | UniProt (P19793) Pfam (PF00105) | HOMO SAPIENS (HUMAN) | NUCLEAR RECEPTOR SUBFAMILY 2 GROUP B MEMBER 1, RETINOID X RECEPTOR ALPHA |
| 2 | C (C) | 5'-D(*TP*GP*GP*GP*GP*TP*CP*AP*GP*AP*GP*TP*TP*CP *AP*AP*TP)-3' | polymer | 17 | 5282.4 | 1 | HOMO SAPIENS | ||
| 3 | D (D) | 5'-D(*AP*TP*TP*GP*AP*AP*CP*TP*CP*TP*GP*AP*CP*CP *CP*CP*AP)-3' | polymer | 17 | 5131.4 | 1 | HOMO SAPIENS | ||
| 4 | E, F, J, K (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 5 | G, H, I, O, R (A, C, D) | CHLORIDE ION | non-polymer | 35.5 | 5 | Chemie (CL) | |||
| 6 | L, M, N, P (C, D) | POTASSIUM ION | non-polymer | 39.1 | 4 | Chemie (K) | |||
| 7 | Q (D) | NITRATE ION | non-polymer | 62.0 | 1 | Chemie (NO3) | |||
| 8 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 315 | Chemie (HOH) |
Sequence modifications
A, B: 130 - 212 (UniProt: P19793)
| PDB | External Database | Details |
|---|---|---|
| Gly 126 | - | expression tag |
| Ser 127 | - | expression tag |
| His 128 | - | expression tag |
| Met 129 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 30939.6 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 657.3 | |
| All* | Total formula weight | 31596.9 |
