4CLP
Crystal structure of human soluble Adenylyl Cyclase complex with adenosine-3',5'-cyclic-monophosphate
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | ADENYLATE CYCLASE TYPE 10 | polymer | 475 | 54269.7 | 1 | UniProt (Q96PN6) Pfam (PF00211) | HOMO SAPIENS (HUMAN) | AH-RELATED PROTEIN, ADENYLATE CYCLASE HOMOLOG, GERM CELL SOLUBLE ADENYLYL CYCLASE, HSAC, SAC, TESTICULAR SOLUBLE ADENYLYL CYCLASE, SOLUBLE ADENYLYL CYCLASE |
| 2 | B, C, D (A) | ACETATE ION | non-polymer | 59.0 | 3 | Chemie (ACT) PubChem (175) | |||
| 3 | E, F (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) PubChem (753) | |||
| 4 | G, H (A) | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 2 | Chemie (CMP) PubChem (23902375) PubChem (25322948) PubChem (40467852) PubChem (44629928) PubChem (176488666) PubChem (25322946) PubChem (59350541) PubChem (274) PubChem (56973690) PubChem (59909322) PubChem (59968988) PubChem (6604194) PubChem (70878457) PubChem (6076) PubChem (216878) PubChem (163043517) PubChem (3080770) PubChem (3246347) PubChem (124132380) PubChem (6603718) PubChem (6713792) PubChem (6714006) PubChem (129317551) PubChem (131841987) PubChem (134693155) PubChem (138107790) PubChem (12071879) PubChem (12866365) PubChem (163043518) | |||
| 5 | I, J, K, L (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 4 | Chemie (EDO) | |||
| 6 | M (A) | DI(HYDROXYETHYL)ETHER | non-polymer | 106.1 | 1 | Chemie (PEG) PubChem (8117) | |||
| 7 | N (A) | water | water | 18.0 | 209 | Chemie (HOH) |
Sequence modifications
A: 1 - 469 (UniProt: Q96PN6)
| PDB | External Database | Details |
|---|---|---|
| His 470 | - | expression tag |
| His 471 | - | expression tag |
| His 472 | - | expression tag |
| His 473 | - | expression tag |
| His 474 | - | expression tag |
| His 475 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 54269.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1374.1 | |
| All* | Total formula weight | 55643.8 |
