4CKU
Three dimensional structure of plasmepsin II in complex with hydroxyethylamine-based inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... | PLASMEPSIN-2 | polymer | 329 | 36909.6 | 6 | UniProt (P46925) Pfam (PF00026) In PDB | PLASMODIUM FALCIPARUM (MALARIA PARASITE P. FALCIPARUM) | ASPARTIC HEMOGLOBINASE II, PFAPD, PLASMEPSIN II |
| 2 | A, B, C, D, E... | 5-[1,1-bis(oxidanylidene)-1,2-thiazinan-2-yl]-N3-[(2S,3R)-4-[2-(3-methoxyphenyl)propan-2-ylamino]-3-oxidanyl-1-phenyl-butan-2-yl]-N1,N1-dipropyl-benzene-1,3-dicarboxamide | non-polymer | 692.9 | 6 | Chemie (P2F) | |||
| 3 | water | water | 18.0 | 1189 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F: 1 - 329 (UniProt: P46925)
| PDB | External Database | Details |
|---|---|---|
| Ser 205 | Met 329 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 221457.7 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 4157.4 | |
| All* | Total formula weight | 225615.1 |
