Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| D | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| D | 0006508 | biological_process | proteolysis |
| E | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| E | 0006508 | biological_process | proteolysis |
| F | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| F | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE P2F A 400 |
| Chain | Residue |
| A | ILE14 |
| A | GLY216 |
| A | THR217 |
| A | SER218 |
| A | ILE300 |
| A | HOH2059 |
| A | HOH2060 |
| A | HOH2182 |
| A | HOH2183 |
| A | ILE32 |
| A | ASP34 |
| A | GLY36 |
| A | TYR77 |
| A | VAL78 |
| A | SER79 |
| A | TYR192 |
| A | ASP214 |
| site_id | AC2 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE P2F B 400 |
| Chain | Residue |
| B | ILE14 |
| B | ILE32 |
| B | ASP34 |
| B | GLY36 |
| B | VAL78 |
| B | SER79 |
| B | PHE111 |
| B | ILE123 |
| B | TYR192 |
| B | ASP214 |
| B | GLY216 |
| B | THR217 |
| B | SER218 |
| B | ILE290 |
| B | LEU292 |
| B | PHE294 |
| B | ILE300 |
| B | HOH2081 |
| B | HOH2218 |
| site_id | AC3 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE P2F C 400 |
| Chain | Residue |
| C | MET15 |
| C | ILE32 |
| C | ASP34 |
| C | GLY36 |
| C | VAL78 |
| C | PHE111 |
| C | TYR192 |
| C | ASP214 |
| C | GLY216 |
| C | THR217 |
| C | SER218 |
| C | ILE290 |
| C | LEU292 |
| C | ILE300 |
| C | HOH2085 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE P2F D 400 |
| Chain | Residue |
| D | MET15 |
| D | ILE32 |
| D | ASP34 |
| D | GLY36 |
| D | VAL78 |
| D | SER79 |
| D | PHE111 |
| D | THR114 |
| D | TYR192 |
| D | ASP214 |
| D | GLY216 |
| D | THR217 |
| D | SER218 |
| D | ILE300 |
| D | HOH2086 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE P2F E 400 |
| Chain | Residue |
| E | MET15 |
| E | ILE32 |
| E | ASP34 |
| E | GLY36 |
| E | TYR77 |
| E | VAL78 |
| E | SER79 |
| E | PHE111 |
| E | ILE123 |
| E | TYR192 |
| E | ASP214 |
| E | GLY216 |
| E | THR217 |
| E | SER218 |
| E | ILE290 |
| E | ILE300 |
| E | HOH2073 |
| E | HOH2182 |
| site_id | AC6 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE P2F F 400 |
| Chain | Residue |
| F | HOH2193 |
| F | MET15 |
| F | ILE32 |
| F | ASP34 |
| F | GLY36 |
| F | SER37 |
| F | VAL78 |
| F | SER79 |
| F | PHE111 |
| F | TYR192 |
| F | ASP214 |
| F | GLY216 |
| F | THR217 |
| F | SER218 |
| F | LEU292 |
| F | HOH2073 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. FILDTGSANLWV |
| Chain | Residue | Details |
| A | PHE31-VAL42 | |
| A | CYS211-VAL222 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | Active site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU10094","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 614 |
| Details | Domain: {"description":"Peptidase A1","evidences":[{"source":"PROSITE-ProRule","id":"PRU01103","evidenceCode":"ECO:0000255"}]} |
