4CI9
Crystal structure of cathepsin A, apo-structure
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | LYSOSOMAL PROTECTIVE PROTEIN | polymer | 455 | 51829.4 | 1 | UniProt (P10619) Pfam (PF00450) | HOMO SAPIENS (HUMAN) | CARBOXYPEPTIDASE C, CARBOXYPEPTIDASE L, CATHEPSIN A, PROTECTIVE PROTEIN CATHEPSIN A, PPCA, PROTECTIVE PROTEIN FOR BETA-GALACTOSIDASE |
| 2 | B, C (B, C) | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 424.4 | 2 | In PDB GlyTouCan (G42666HT) | |||
| 3 | D (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 4 | E, F (A) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 5 | G, H (A) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 6 | I (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 7 | J (A) | water | water | 18.0 | 614 | Chemie (HOH) |
Sequence modifications
A: 1 - 452 (UniProt: P10619)
| PDB | External Database | Details |
|---|---|---|
| Ser -1 | - | expression tag |
| Arg 0 | - | expression tag |
| Glu 453 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 51829.4 | |
| Branched | Number of molecules | 2 |
| Total formula weight | 848.8 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 476.5 | |
| All* | Total formula weight | 53154.6 |
