4CHB
Crystal structure of the human KLHL2 Kelch domain in complex with a WNK4 peptide
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | KELCH-LIKE PROTEIN 2 | polymer | 302 | 32830.3 | 2 | UniProt (O95198) Pfam (PF01344) | HOMO SAPIENS (HUMAN) | ACTIN-BINDING PROTEIN MAYVEN |
| 2 | C, D (C, D) | SERINE/THREONINE-PROTEIN KINASE WNK4 | polymer | 11 | 1309.3 | 2 | UniProt (Q96J92) | HOMO SAPIENS | PROTEIN KINASE LYSINE-DEFICIENT 4, PROTEIN KINASE WITH NO LYSINE 4 |
| 3 | E, G, K, L, N... (A, B, C, D) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 6 | Chemie (EDO) | |||
| 4 | F, I, J, M (A, B) | SULFATE ION | non-polymer | 96.1 | 4 | Chemie (SO4) | |||
| 5 | H (A) | DODECAETHYLENE GLYCOL | non-polymer | 546.6 | 1 | Chemie (12P) | |||
| 6 | P, Q, R (A, B, C) | water | water | 18.0 | 296 | Chemie (HOH) |
Sequence modifications
A, B: 294 - 591 (UniProt: O95198)
| PDB | External Database | Details |
|---|---|---|
| Ser 292 | - | expression tag |
| Met 293 | - | expression tag |
| Arg 592 | - | expression tag |
| Leu 593 | - | expression tag |
| Val 457 | Gly 457 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 68279.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1303.3 | |
| All* | Total formula weight | 69582.4 |
