4CH8
High-salt crystal structure of a thrombin-GpIbalpha peptide complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C, E, G (A, C, E, G) | THROMBIN, LIGHT CHAIN | polymer | 36 | 4096.5 | 4 | UniProt (P00734) Pfam (PF09396) | HOMO SAPIENS (HUMAN) | COAGULATION FACTOR II |
| 2 | B, D, F, H (B, D, F, H) | THROMBIN, HEAVY CHAIN | polymer | 259 | 29780.2 | 4 | UniProt (P00734) Pfam (PF00089) | HOMO SAPIENS (HUMAN) | |
| 3 | I, J, K, L (P, Q, R, S) | PLATELET GLYCOPROTEIN IB ALPHA CHAIN, RESIDUES 287-300 | polymer | 14 | 1935.6 | 4 | UniProt (P07359) | HOMO SAPIENS | GP-IB ALPHA, GPIB-ALPHA, GPIBA, GLYCOPROTEIN IBALPHA, ANTIGEN CD42B-ALPHA, GPIBALPHA PEPTIDE |
| 4 | M, P, R, U (B, D, F, H) | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 5 | N, Q, S, V (B, D, F, H) | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide | non-polymer | 454.0 | 4 | BIRD (PRD_000020) Chemie (0G6) | |||
| 6 | O, T (B, F) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 7 | AA, BA, CA, DA, W... (E, F, G, H, A...) | water | water | 18.0 | 424 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 143249.3 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 2092.1 | |
| All* | Total formula weight | 145341.4 |
