4CFK
N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH LY294002
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BRD4 PROTEIN | polymer | 127 | 15099.4 | 1 | UniProt (Q6NXE4) Pfam (PF00439) UniProt (by SIFTS) (O60885) | HOMO SAPIENS (HUMAN) | BROMODOMAIN CONTAINING PROTEIN 4 |
| 2 | B (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 3 | C (A) | 2-MORPHOLIN-4-YL-7-PHENYL-4H-CHROMEN-4-ONE | non-polymer | 307.3 | 1 | Chemie (LY2) | |||
| 4 | D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 1 | Chemie (EDO) | |||
| 5 | E (A) | water | water | 18.0 | 238 | Chemie (HOH) |
Sequence modifications
A: 42 - 168 (UniProt: Q6NXE4)
| PDB | External Database | Details |
|---|---|---|
| Met 43 | Thr 43 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15099.4 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 461.5 | |
| All* | Total formula weight | 15560.9 |
