4CFG

Structure of the TRIM25 coiled-coil

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	E3 UBIQUITIN/ISG15 LIGASE TRIM25	polymer	630	71448.5	2	UniProt (Q14258) Pfam (PF13445) Pfam (PF13765) Pfam (PF00622) In PDB	HOMO SAPIENS (HUMAN)	ESTROGEN-RESPONSIVE FINGER PROTEIN, RING FINGER PROTEIN 147, TRIPARTITE MOTIF-CONTAINING PROTEIN 25, UBIQUITIN/ISG15-CONJUGATING ENZYME TRIM25, ZINC FINGER PROTEIN 147, TRIM
2		water	water		18.0	8	Chemie (HOH)

Sequence modifications

A, B: 1 - 630 (UniProt: Q14258)

PDB	External Database	Details
Gln 273	Lys 273	engineered mutation
Gln 320	Lys 320	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	142897.0
All*	Total formula weight	142897.0

*Water molecules are not included.