4CDR
Human O-GlcNAc transferase in complex with a bisubstrate inhibitor, Goblin1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT | polymer | 723 | 80974.5 | 4 | UniProt (O15294) Pfam (PF13424) Pfam (PF13414) Pfam (PF13844) | HOMO SAPIENS (HUMAN) | O-GLCNAC TRANSFERASE SUBUNIT P110, O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE 110 KDA SUBUNIT, OGT, O-GLCNAC TRANSFERASE |
| 2 | E, F, G, H (E, F, G, H) | GOBLIN1 | polymer | 9 | 755.9 | 4 | BIRD (PRD_002043) | SYNTHETIC CONSTRUCT | |
| 3 | AA, BA, CA, DA, EA... (C, D, A, E, F...) | SULFATE ION | non-polymer | 96.1 | 31 | Chemie (SO4) | |||
| 4 | KA, MA, OA, PA (E, F, G, H) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 4 | Chemie (UDP) |
Sequence modifications
A, B, C, D: 313 - 1031 (UniProt: O15294)
| PDB | External Database | Details |
|---|---|---|
| Gly 309 | - | expression tag |
| Pro 310 | - | expression tag |
| Gly 311 | - | expression tag |
| Ser 312 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 326921.5 | |
| Non-Polymers* | Number of molecules | 35 |
| Total formula weight | 4594.6 | |
| All* | Total formula weight | 331516.1 |
