4CDR
Human O-GlcNAc transferase in complex with a bisubstrate inhibitor, Goblin1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | UDP-N-ACETYLGLUCOSAMINE--PEPTIDE N-ACETYLGLUCOSAMINYLTRANSFERASE 110 KDA SUBUNIT | polymer | 723 | 80974.5 | 4 | UniProt (O15294) Pfam (PF13424) Pfam (PF13414) Pfam (PF13844) | HOMO SAPIENS (HUMAN) | O-GLCNAC TRANSFERASE SUBUNIT P110, O-LINKED N-ACETYLGLUCOSAMINE TRANSFERASE 110 KDA SUBUNIT, OGT, O-GLCNAC TRANSFERASE |
| 2 | E, F, G, H (E, F, G, H) | GOBLIN1 | polymer | 9 | 755.9 | 4 | BIRD (PRD_002043) | SYNTHETIC CONSTRUCT | |
| 3 | AA, BA, CA, DA, EA... (C, D, A, E, F...) | SULFATE ION | non-polymer | 96.1 | 31 | Chemie (SO4) | |||
| 4 | KA, MA, OA, PA (E, F, G, H) | URIDINE-5'-DIPHOSPHATE | non-polymer | 404.2 | 4 | Chemie (UDP) PubChem (1158) PubChem (6031) PubChem (25323044) PubChem (25323048) PubChem (44298965) PubChem (53486216) PubChem (60098857) PubChem (57448939) PubChem (3084486) PubChem (91746160) PubChem (6101632) PubChem (92332560) PubChem (92332561) PubChem (92332562) PubChem (92332563) PubChem (93088131) PubChem (93630083) PubChem (6604175) PubChem (11811538) PubChem (12049241) |
Sequence modifications
A, B, C, D: 313 - 1031 (UniProt: O15294)
| PDB | External Database | Details |
|---|---|---|
| Gly 309 | - | expression tag |
| Pro 310 | - | expression tag |
| Gly 311 | - | expression tag |
| Ser 312 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 326921.5 | |
| Non-Polymers* | Number of molecules | 35 |
| Total formula weight | 4594.6 | |
| All* | Total formula weight | 331516.1 |
