4CCZ
Crystal structure of human 5-methyltetrahydrofolate-homocysteine methyltransferase, the homocysteine and folate binding domains
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | METHIONINE SYNTHASE | polymer | 644 | 70523.8 | 1 | UniProt (Q99707) Pfam (PF02574) Pfam (PF00809) | HOMO SAPIENS (HUMAN) | 5-METHYLTETRAHYDROFOLATE--HOMOCYSTEINE METHYLTRANSFERASE, VITAMIN-B12 DEPENDENT METHIONINE SYNTHASE, MS |
| 2 | B (A) | (6S)-5,6,7,8-TETRAHYDROFOLATE | non-polymer | 445.4 | 1 | Chemie (THG) | |||
| 3 | C (A) | water | water | 18.0 | 2 | Chemie (HOH) |
Sequence modifications
A: 16 - 657 (UniProt: Q99707)
| PDB | External Database | Details |
|---|---|---|
| Ser 14 | - | expression tag |
| Met 15 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 70523.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 445.4 | |
| All* | Total formula weight | 70969.3 |
