4CC4

Complex of InlC of Listeria monocytogenes and human Tuba C-terminal SH3 domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, E (A, E)	INLC PROTEIN	polymer	266	29718.5	2	UniProt (P71451) Pfam (PF12354) Pfam (PF12799) Pfam (PF08191)	LISTERIA MONOCYTOGENES EGD-E	INLC, INTERNALIN, INTERNALIN B, INTERNALIN C
2	B, D, F (B, D, F)	DYNAMIN-BINDING PROTEIN	polymer	68	7783.7	3	UniProt (Q6XZF7) Pfam (PF07653)	HOMO SAPIENS (HUMAN)	TUBA SH3-6, SCAFFOLD PROTEIN TUBA
3	C (C)	INLC PROTEIN	polymer	266	29702.5	1	UniProt (P71451) Pfam (PF12354) Pfam (PF12799) Pfam (PF08191)	LISTERIA MONOCYTOGENES EGD-E	INLC, INTERNALIN, INTERNALIN B, INTERNALIN C
4	G, I, J, P, T (A, B, C, D, F)	GLYCEROL	non-polymer		92.1	5	Chemie (GOL)
5	H, N, O, Q, U... (A, C, D, F)	CHLORIDE ION	non-polymer		35.5	6	Chemie (CL)
6	K (C)	2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL	non-polymer		354.4	1	Chemie (PE4)
7	L, M (C)	SULFATE ION	non-polymer		96.1	2	Chemie (SO4)
8	R, S (E)	PHOSPHATE ION	non-polymer		95.0	2	Chemie (PO4)
9	AA, BA, W, X, Y... (E, F, A, B, C...)	water	water		18.0	280	Chemie (HOH)

Sequence modifications

A, E: 35 - 297 (UniProt: P71451)

PDB	External Database	Details
Ala 33	-	expression tag
Ser 34	-	expression tag
Ala 246	Tyr 246	engineered mutation
Ala 247	Tyr 247	engineered mutation
Lys 298	-	expression tag

B, D, F: 1513 - 1577 (UniProt: Q6XZF7)

PDB	External Database	Details
Gly 1511	-	expression tag
Pro 1512	-	expression tag
Ala 1578	-	expression tag

C: 35 - 297 (UniProt: P71451)

PDB	External Database	Details
Ala 33	-	expression tag
Ser 34	-	expression tag
Ala 246	Tyr 246	engineered mutation
Ala 247	Tyr 247	engineered mutation
Lys 298	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	112490.7
Non-Polymers*	Number of molecules	16
	Total formula weight	1409.7
All*	Total formula weight	113900.4

*Water molecules are not included.