4CBS
X-ray structure of quintuple mutant of human alanine glyoxylate aminotransferase, AGXT_RHEAM
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | SERINE--PYRUVATE AMINOTRANSFERASE | polymer | 392 | 43147.0 | 1 | UniProt (P21549) Pfam (PF00266) | HOMO SAPIENS (HUMAN) | SPT, ALANINE--GLYOXYLATE AMINOTRANSFERASE, AGT, ALANINE GLYOXYLATE AMINOTRANSFERASE |
| 2 | B (A) | PYRIDOXAL-5'-PHOSPHATE | non-polymer | 247.1 | 1 | Chemie (PLP) | |||
| 3 | C (A) | water | water | 18.0 | 82 | Chemie (HOH) |
Sequence modifications
A: 1 - 392 (UniProt: P21549)
| PDB | External Database | Details |
|---|---|---|
| Arg 23 | Gln 23 | engineered mutation |
| His 48 | Ser 48 | engineered mutation |
| Glu 52 | Asp 52 | engineered mutation |
| Ala 113 | Val 113 | engineered mutation |
| Met 340 | Ile 340 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 43147.0 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 247.1 | |
| All* | Total formula weight | 43394.1 |
