4CBQ
Crystal structure of the thioredoxin reductase from Entamoeba histolytica with auranofin Au(I) bound to Cys286
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | THIOREDOXIN REDUCTASE | polymer | 314 | 33779.6 | 2 | UniProt (C4LW95) Pfam (PF07992) | ENTAMOEBA HISTOLYTICA | |
| 2 | C, I (A, B) | NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | non-polymer | 745.4 | 2 | Chemie (NDP) | |||
| 3 | D, E, F, J, K (A, B) | SULFATE ION | non-polymer | 96.1 | 5 | Chemie (SO4) | |||
| 4 | G, L (A, B) | GOLD ION | non-polymer | 197.0 | 2 | Chemie (AU) | |||
| 5 | H, O (A, B) | FLAVIN-ADENINE DINUCLEOTIDE | non-polymer | 785.5 | 2 | Chemie (FAD) | |||
| 6 | M, N (B) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 7 | P, Q (A, B) | water | water | 18.0 | 417 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 67559.2 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 4007.1 | |
| All* | Total formula weight | 71566.3 |
