4CBM

Pestivirus NS3 helicase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	SERINE PROTEASE NS3	polymer	516	58024.1	4	UniProt (P19712) Pfam (PF07652) Pfam (PF00271) Pfam (PF20907)	CLASSICAL SWINE FEVER VIRUS	NON-STRUCTURAL PROTEIN 3
2	E (A)	water	water		18.0	1	Chemie (HOH)

Sequence modifications

A, B, C, D: 193 - 691 (UniProt: P19712)

PDB	External Database	Details
Met 176	-	expression tag
Ala 177	-	expression tag
Ser 178	-	expression tag
His 179	-	expression tag
His 180	-	expression tag
His 181	-	expression tag
His 182	-	expression tag
His 183	-	expression tag
His 184	-	expression tag
His 185	-	expression tag
Glu 186	-	expression tag
Asn 187	-	expression tag
Leu 188	-	expression tag
Tyr 189	-	expression tag
Phe 190	-	expression tag
Gln 191	-	expression tag
Gly 192	-	expression tag
Lys 600	Gln 2189	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	232096.3
All*	Total formula weight	232096.3

*Water molecules are not included.