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4CA1

Crystal structure of Siah1 at 1.58 A resolution.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
E3 UBIQUITIN-PROTEIN LIGASE SIAH1polymer19521921.12UniProt (Q8IUQ4)
Pfam (PF21361)
Pfam (PF03145)
HOMO SAPIENS (HUMAN)SEVEN IN ABSENTIA HOMOLOG 1, SIAH-1, SIAH-1A
2C, D, P, Q
(A, B)
ZINC IONnon-polymer65.44Chemie (ZN)
3E, F, G, R, S
(A, B)
SULFATE IONnon-polymer96.15Chemie (SO4)
4H, O, T
(A, B)
CHLORIDE IONnon-polymer35.53Chemie (CL)
5I, J, K, L, M...
(A, B)
GLYCEROLnon-polymer92.112Chemie (GOL)
6AA, BA
(A, B)
waterwater18.0331Chemie (HOH)
Sequence modifications
A, B: 91 - 282 (UniProt: Q8IUQ4)
PDBExternal DatabaseDetails
Gly 88-expression tag
His 89-expression tag
Met 90-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight43842.2
Non-Polymers*Number of molecules24
Total formula weight1953.4
All*Total formula weight45795.6
*Water molecules are not included.

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PDB entries from 2025-12-17

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