4C9R

Xenopus ZNRF3 ectodomain in complex with Xenopus RSPO2 Fu1-Fu2 crystal form I

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	E3 UBIQUITIN-PROTEIN LIGASE ZNRF3	polymer	182	20494.0	2	UniProt (Q08D68) Pfam (PF18212)	XENOPUS (SILURANA) TROPICALIS (WESTERN CLAWED FROG)	ZINC/RING FINGER PROTEIN 3, ZNRF3
2	B, D (B, D)	R-SPONDIN-2	polymer	121	13781.7	2	UniProt (Q5M7L6) Pfam (PF15913)	XENOPUS (SILURANA) TROPICALIS (WESTERN CLAWED FROG)	ROOF PLATE-SPECIFIC SPONDIN-2, RSPO2
3	E, F, G, H (A, B, C, D)	water	water		18.0	220	Chemie (HOH)

Sequence modifications

A, C: 24 - 191 (UniProt: Q08D68)

PDB	External Database	Details
Glu 22	-	expression tag
Thr 23	-	expression tag
Gly 192	-	expression tag
Thr 193	-	expression tag
His 194	-	expression tag
His 195	-	expression tag
His 196	-	expression tag
His 197	-	expression tag
His 198	-	expression tag
His 199	-	expression tag
His 200	-	expression tag
His 201	-	expression tag
His 202	-	expression tag
His 203	-	expression tag

B, D: 35 - 144 (UniProt: Q5M7L6)

PDB	External Database	Details
Glu 32	-	expression tag
Thr 33	-	expression tag
Gly 34	-	expression tag
Thr 145	-	expression tag
Lys 146	-	expression tag
His 147	-	expression tag
His 148	-	expression tag
His 149	-	expression tag
His 150	-	expression tag
His 151	-	expression tag
His 152	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	68551.5
All*	Total formula weight	68551.5

*Water molecules are not included.