4C9Q

Structure of yeast mitochondrial ADP/ATP carrier isoform 3 inhibited by carboxyatractyloside (P21 crystal form)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	ADP, ATP CARRIER PROTEIN 3	polymer	322	35256.0	2	UniProt (P18238) Pfam (PF00153)	SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)	ADP/ATP TRANSLOCASE 3, ADENINE NUCLEOTIDE TRANSLOCATOR 3, ANT 3, ADP-ATP CARRIER ISOFORM 3
2	C, G (A, B)	Carboxyatractyloside	non-polymer		770.8	2	Chemie (CXT) PubChem (36404) PubChem (16760342) PubChem (20055804) PubChem (21118350) PubChem (23620300) PubChem (49866850) PubChem (108174) PubChem (10078913) PubChem (102004836) PubChem (125181477) PubChem (129539659) PubChem (131698233) PubChem (118855619) PubChem (125181478) PubChem (125181479) PubChem (127256228) PubChem (14681645) PubChem (132285300) PubChem (154805982) PubChem (154828161) PubChem (146158621) PubChem (163092075) PubChem (171156833)
3	D, E, F, H, I... (A, B)	CARDIOLIPIN	non-polymer		1464.0	6	Chemie (CDL) PubChem (17753886) PubChem (5287898)

Sequence modifications

A, B: 3 - 307 (UniProt: P18238)

PDB	External Database	Details
Met -14	-	expression tag
His -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
Ile -4	-	expression tag
Glu -3	-	expression tag
Gly -2	-	expression tag
Arg -1	-	expression tag
Ser 0	-	expression tag
Met 1	-	expression tag
Ala 2	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	70512.0
Non-Polymers*	Number of molecules	8
	Total formula weight	10325.9
All*	Total formula weight	80837.9

*Water molecules are not included.