4C9E

Mouse ZNRF3 ectodomain in complex with Xenopus RSPO2 Fu1-Fu2 (Seleno Met) crystal form II

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C, E, G (A, C, E, G)	E3 UBIQUITIN-PROTEIN LIGASE ZNRF3	polymer	165	18203.6	4	UniProt (Q5SSZ7) Pfam (PF18212)	MUS MUSCULUS (HOUSE MOUSE)	ZNRF3, ZINC/RING FINGER PROTEIN 3
2	B, D, F, H (B, D, F, H)	R-SPONDIN-2	polymer	121	13828.6	4	UniProt (Q5M7L6) Pfam (PF15913)	XENOPUS (SILURANA) TROPICALIS (WESTERN CLAWED FROG)	RSPO2, ROOF PLATE-SPECIFIC SPONDIN-2

Sequence modifications

A, C, E, G: 53 - 205 (UniProt: Q5SSZ7)

PDB	External Database	Details
Glu 50	-	expression tag
Thr 51	-	expression tag
Gly 52	-	expression tag
Gly 206	-	expression tag
Thr 207	-	expression tag
Lys 208	-	expression tag
His 209	-	expression tag
His 210	-	expression tag
His 211	-	expression tag
His 212	-	expression tag
His 213	-	expression tag
His 214	-	expression tag

B, D, F, H: 35 - 144 (UniProt: Q5M7L6)

PDB	External Database	Details
Glu 32	-	expression tag
Thr 33	-	expression tag
Gly 34	-	expression tag
Thr 145	-	expression tag
Lys 146	-	expression tag
His 147	-	expression tag
His 148	-	expression tag
His 149	-	expression tag
His 150	-	expression tag
His 151	-	expression tag
His 152	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	8
	Total formula weight	128128.8
All*	Total formula weight	128128.8

*Water molecules are not included.