4C53

Crystal Structure of Guanarito virus GP2 in the post-fusion conformation

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C	PRE-GLYCOPROTEIN POLYPROTEIN GP COMPLEX	polymer	138	16285.4	3	UniProt (A1A3Z2) Pfam (PF00798) UniProt (by SIFTS) (Q8AYW1) In PDB	GUANARITO VIRUS	GTOV GP2
2	D	beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		586.5	1	In PDB GlyTouCan (G15407YE)
3	E	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		424.4	1	In PDB GlyTouCan (G42666HT)
4	F, G, H	alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose	branched		1235.1	3	In PDB GlyTouCan (G55220VL)
5	A, B	2-acetamido-2-deoxy-beta-D-glucopyranose	non-polymer		221.2	3	Chemie (NAG)

Sequence modifications

A, B, C: 292 - 418 (UniProt: A1A3Z2)

PDB	External Database	Details
Thr 290	-	expression tag
Gly 291	-	expression tag
Gly 419	-	expression tag
Thr 420	-	expression tag
Lys 421	-	expression tag
His 422	-	expression tag
His 423	-	expression tag
His 424	-	expression tag
His 425	-	expression tag
His 426	-	expression tag
His 427	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	48856.2
Branched	Number of molecules	5
	Total formula weight	4716.3
Non-Polymers*	Number of molecules	3
	Total formula weight	663.6
All*	Total formula weight	54236.0

*Water molecules are not included.