4C52
Crystal structure of Bcl-xL in complex with benzoylurea compound (39b)
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | BCL-2-LIKE PROTEIN 1 | polymer | 158 | 17918.0 | 2 | UniProt (Q07817) Pfam (PF02180) Pfam (PF00452) In PDB | HOMO SAPIENS (HUMAN) | BCL2-L-1, APOPTOSIS REGULATOR BCL-X |
2 | A, B | (R)-2-(3-(3-((2,4-DIFLUOROPENYL)ETHYNYL)BENZOYL)-3-PROPYLUREIDO)-3-(ISOBUTYLTHIO) PROPANOIC ACID | non-polymer | 502.6 | 2 | Chemie (X0D) | |||
3 | A, B | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
4 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 12 | Chemie (EDO) | |||
5 | water | water | 18.0 | 133 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 26 (UniProt: Q07817)
PDB | External Database | Details |
---|---|---|
Gly -5 | - | expression tag |
Pro -4 | - | expression tag |
Leu -3 | - | expression tag |
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 35835.9 | |
Non-Polymers* | Number of molecules | 21 |
Total formula weight | 2422.4 | |
All* | Total formula weight | 38258.3 |