Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0042981 | biological_process | regulation of apoptotic process |
| B | 0042981 | biological_process | regulation of apoptotic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE X0D A 300 |
| Chain | Residue |
| A | TYR101 |
| A | GLY147 |
| A | LEU150 |
| A | ALA104 |
| A | LEU112 |
| A | PHE123 |
| A | VAL126 |
| A | VAL127 |
| A | LEU130 |
| A | PHE143 |
| A | PHE146 |
| site_id | AC2 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE X0D B 300 |
| Chain | Residue |
| A | ARG102 |
| B | TYR101 |
| B | ARG103 |
| B | ALA104 |
| B | LEU112 |
| B | PHE123 |
| B | VAL126 |
| B | LEU130 |
| B | PHE143 |
| B | PHE146 |
| B | GLY147 |
| B | MET170 |
| B | HOH2048 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1199 |
| Chain | Residue |
| B | ASN136 |
| B | ARG139 |
| B | HOH2044 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1197 |
| Chain | Residue |
| A | ARG6 |
| A | VAL10 |
| A | TRP24 |
| B | SER-1 |
| B | MET1 |
| B | SER2 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1200 |
| Chain | Residue |
| B | ALA119 |
| B | TYR120 |
| B | ARG165 |
| B | TRP169 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1198 |
| Chain | Residue |
| A | SER-1 |
| A | GLY-2 |
| A | GLU7 |
| B | TRP24 |
| B | SER25 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1199 |
| Chain | Residue |
| A | LYS157 |
| B | ARG132 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1200 |
| Chain | Residue |
| A | ASN136 |
| A | ARG139 |
| site_id | AC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1201 |
| Chain | Residue |
| A | GLU124 |
| A | GLN125 |
| A | ASN128 |
| A | HIS177 |
| B | ASN175 |
| B | ASP176 |
| B | HOH2066 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1201 |
| Chain | Residue |
| B | ASN136 |
| B | TRP137 |
| B | GLY138 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1202 |
| Chain | Residue |
| A | ASN136 |
| A | TRP137 |
| A | GLY138 |
| A | TYR195 |
| site_id | BC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 1203 |
| Chain | Residue |
| A | THR115 |
| A | PRO116 |
| A | HOH2037 |
| B | PHE131 |
| B | TYR173 |
| B | HIS177 |
| B | HOH2039 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1204 |
| Chain | Residue |
| A | GLY-5 |
| A | GLN3 |
| A | HOH2067 |
| B | GLU179 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1207 |
| Chain | Residue |
| A | ASN128 |
| A | VAL135 |
| A | TYR173 |
| A | HIS177 |
| B | HOH2066 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1202 |
| Chain | Residue |
| A | LEU-3 |
| B | SER25 |
| B | GLN26 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1203 |
| Chain | Residue |
| A | SER110 |
| B | GLN121 |
| B | GLU124 |
| B | GLN125 |
| B | HOH2040 |
| site_id | BC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE EDO B 1204 |
| Chain | Residue |
| B | GLU98 |
| B | ARG102 |
| site_id | BC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1205 |
| Chain | Residue |
| A | SER14 |
| A | ALA84 |
| A | LYS87 |
| B | GLU7 |
| site_id | CC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO A 1206 |
| Chain | Residue |
| A | GLN88 |
| A | ARG91 |
| B | TYR15 |
| B | ARG91 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1205 |
| Chain | Residue |
| A | ASP11 |
| A | ARG91 |
| B | ARG91 |
| site_id | CC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO B 1206 |
| Chain | Residue |
| B | THR115 |
| B | TYR15 |
| B | SER18 |
Functional Information from PROSITE/UniProt
| site_id | PS01080 |
| Number of Residues | 19 |
| Details | BH1 Apoptosis regulator, Bcl-2 family BH1 motif signature. LFrDGv.NWGRIVAFFsFGG |
| Chain | Residue | Details |
| A | LEU130-GLY148 | |
| site_id | PS01258 |
| Number of Residues | 12 |
| Details | BH2 Apoptosis regulator, Bcl-2 family BH2 motif signature. WIqenGGWDtFV |
| Chain | Residue | Details |
| A | TRP181-VAL192 | |
| site_id | PS01259 |
| Number of Residues | 15 |
| Details | BH3 Apoptosis regulator, Bcl-2 family BH3 motif signature. VkqaLReAGDEFELR |
| Chain | Residue | Details |
| A | VAL86-ARG100 | |
| site_id | PS01260 |
| Number of Residues | 21 |
| Details | BH4_1 Apoptosis regulator, Bcl-2 family BH4 motif signature. SNRELVvDFLSYKLSQKGYsW |
| Chain | Residue | Details |
| A | SER4-TRP24 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by caspase-1 |
| Chain | Residue | Details |
| A | GLY117 | |
| B | GLY117 | |
| Chain | Residue | Details |
| A | PHE105 | |
| B | PHE105 | |
| Chain | Residue | Details |
| A | THR118 | |
| B | THR118 | |
