4C3P
Structure of dephosphorylated Aurora A (122-403) bound to TPX2 and AMPPCP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, D) | AURORA KINASE A | polymer | 282 | 32689.5 | 2 | UniProt (O14965) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | AURORA 2, AURORA/IPL1-RELATED KINASE 1, ARK-1, AURORA-RELAT ED KINASE 1, HARK1, BREAST TUMOR-AMPLIFIED KINASE, SERINE/THREONIN E- PROTEIN KINASE 15, SERINE/THREONINE-PROTEIN KINASE 6, SERINE/THR EONINE-PROTEIN KINASE AURORA-A, AURORA A KINASE |
| 2 | B, D (B, E) | TARGETING PROTEIN FOR XKLP2 | polymer | 43 | 4927.1 | 2 | UniProt (Q9ULW0) Pfam (PF09041) | HOMO SAPIENS (HUMAN) | DIFFERENTIALLY EXPRESSED IN CANCEROUS AND NON-CANCEROUS LUN G CELLS 2, DIL-2, HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN 519, PROTEIN FLS353, RESTRICTED EXPRESSION PROLIFERATION-ASSOCIATED PR OTEIN 100, P100, TARGETING PROTEIN FOR XKLP2, TPX2 |
| 3 | E, F (A, D) | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | non-polymer | 505.2 | 2 | Chemie (ACP) | |||
| 4 | G (D) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 5 | H, I, J (A, B, D) | water | water | 18.0 | 21 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 75233.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 1106.5 | |
| All* | Total formula weight | 76339.6 |
