4C3J
Structure of 14-subunit RNA polymerase I at 3.35 A resolution, crystal form C2-90
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA190 | polymer | 1664 | 186677.0 | 1 | UniProt (P10964) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) Pfam (PF04998) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | DNA-DIRECTED RNA POLYMERASE I 190 KDA POLYPEPTIDE, A190, DN A-DIRECTED RNA POLYMERASE I LARGEST SUBUNIT, DNA-DIRECTED RNA POLY MERASE I SUBUNIT A190 |
| 2 | B (B) | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 | polymer | 1203 | 135910.3 | 1 | UniProt (P22138) Pfam (PF00562) Pfam (PF04560) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF06883) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | DNA-DIRECTED RNA POLYMERASE I 135 KDA POLYPEPTIDE, A135, DN A-DIRECTED RNA POLYMERASE I POLYPEPTIDE 2, RNA POLYMERASE I SUBUNIT 2, DNA-DIRECTED RNA POLYMERASE I SUBUNIT A135 |
| 3 | C (C) | DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1 | polymer | 335 | 37732.6 | 1 | UniProt (P07703) Pfam (PF01193) Pfam (PF01000) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I AND III SUBUNIT AC1, C37, DNA-DIRECTED RN A POLYMERASES I AND III 40 KDA POLYPEPTIDE, AC40, C40, DNA-DIRECTED RNA POLYMERASE I SUBUNIT AC40 |
| 4 | D (D) | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14 | polymer | 137 | 14585.1 | 1 | UniProt (P50106) Pfam (PF08203) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | A14, DNA-DIRECTED RNA POLYMERASE I 14 KDA POLYPEPTIDE, DNA- DIRECTED RNA POLYMERASE I SUBUNIT A14 |
| 5 | E (E) | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC1 | polymer | 215 | 25117.1 | 1 | UniProt (P20434) Pfam (PF03871) Pfam (PF01191) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I, II, AND III SUBUNIT ABC1, ABC27, DNA-DIR ECTED RNA POLYMERASES I, II, AND III 27 KDA POLYPEPTIDE, DNA-DIREC TED RNA POLYMERASE I SUBUNIT ABC27 |
| 6 | F (F) | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC2 | polymer | 155 | 17931.8 | 1 | UniProt (P20435) Pfam (PF01192) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I, II, AND III SUBUNIT ABC2, ABC23, DNA-DIR ECTED RNA POLYMERASES I, II, AND III 23 KDA POLYPEPTIDE, DNA-DIREC TED RNA POLYMERASE I SUBUNIT ABC23 |
| 7 | G (G) | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43 | polymer | 326 | 36264.9 | 1 | UniProt (P46669) Pfam (PF03876) Pfam (PF17875) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | A43, DNA-DIRECTED DNA-DEPENDENT RNA POLYMERASE 36 KDA POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE I SUBUNIT A43 |
| 8 | H (H) | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC3 | polymer | 146 | 16525.4 | 1 | UniProt (P20436) Pfam (PF03870) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I, II, AND III SUBUNIT ABC3, ABC14.4, ABC14.5, DNA-DIRECTED RNA POLYMERASES I, II, AND III 14.5 KDA POLYPE DE, DNA-DIRECTED RNA POLYMERASE I SUBUNIT ABC14.5 |
| 9 | I (I) | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12 | polymer | 125 | 13676.6 | 1 | UniProt (P32529) Pfam (PF02150) Pfam (PF01096) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | A12, A12.2, DNA-DIRECTED RNA POLYMERASE I 13.7 KDA POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE I SUBUNIT A12.2 |
| 10 | J (J) | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC5 | polymer | 70 | 8290.7 | 1 | UniProt (P22139) Pfam (PF01194) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I, II, AND III SUBUNIT ABC5, ABC10-BETA, AB C8, DNA-DIRECTED RNA POLYMERASES I, II, AND III 8.3 KDA POLYPEPTID E, DNA-DIRECTED RNA POLYMERASE I SUBUNIT ABC10-BETA |
| 11 | K (K) | DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2 | polymer | 142 | 16167.9 | 1 | UniProt (P28000) Pfam (PF13656) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I AND III SUBUNIT AC2, AC19, DNA-DIRECTED RNA POLYMERASES I AND III 16 KDA POLYPEPTIDE, RPA19, DNA-DIRECTED RNA POLYMERASE I SUBUNIT AC19 |
| 12 | L (L) | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC4 | polymer | 70 | 7730.0 | 1 | UniProt (P40422) Pfam (PF03604) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I, II, AND III SUBUNIT ABC4, ABC10-ALPHA, DNA-DIRECTED RNA POLYMERASE I SUBUNIT ABC10-ALPHA |
| 13 | M (M) | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 | polymer | 415 | 46721.7 | 1 | UniProt (Q01080) Pfam (PF06870) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | A49, DNA-DIRECTED RNA POLYMERASE I 49 KDA POLYPEPTIDE, DNA- DIRECTED RNA POLYMERASE I SUBUNIT A49 |
| 14 | N (N) | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA34 | polymer | 233 | 26933.5 | 1 | UniProt (P47006) Pfam (PF08208) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | A34, DNA-DIRECTED DNA-DEPENDENT RNA POLYMERASE 34.5 KDA POL YPEPTIDE, A34.5, DNA-DIRECTED RNA POLYMERASE I SUBUNIT A34.5 |
| 15 | O, P, Q, R, S... (A, B, I, J, L) | ZINC ION | non-polymer | 65.4 | 7 | Chemie (ZN) |
Sequence modifications
D: 1 - 137 (UniProt: P50106)
| PDB | External Database | Details |
|---|---|---|
| Ser 12 | Thr 12 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 14 |
| Total formula weight | 590264.5 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 457.9 | |
| All* | Total formula weight | 590722.4 |
