4C2W
Crystal structure of Aurora B in complex with AMP-PNP
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | AURORA KINASE B-A | polymer | 279 | 33005.3 | 2 | UniProt (Q6DE08) Pfam (PF00069) | XENOPUS LAEVIS (AFRICAN CLAWED FROG) | AURORA/IPL1-RELATED KINASE 2-A, AIRK2-A, XAIRK2-A, SERINE/THREONINE-PROTEIN KINASE 12-A, SERINE/THREONINE-PROTEIN KINASE AURO RA-B-A, XAURORA-B, PROTEIN KINASE |
| 2 | C, D (C, D) | INNER CENTROMERE PROTEIN A | polymer | 52 | 6167.1 | 2 | UniProt (O13024) Pfam (PF03941) | XENOPUS LAEVIS (AFRICAN CLAWED FROG) | XL-INCENP, XINC, XINCENP, MITOTIC PHOSPHOPROTEIN 130, PROTEIN KINASE |
| 3 | E, F (A, B) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 2 | Chemie (ANP) | |||
| 4 | G, H, I, J (A, B, C, D) | water | water | 18.0 | 702 | Chemie (HOH) |
Sequence modifications
C, D: 797 - 847 (UniProt: O13024)
| PDB | External Database | Details |
|---|---|---|
| Ile 796 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 78344.8 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 1012.4 | |
| All* | Total formula weight | 79357.2 |
