4C2M
Structure of RNA polymerase I at 2.8 A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, P (1, L) | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 4 | polymer | 70 | 7730.0 | 2 | UniProt (P40422) Pfam (PF03604) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I\,II\,AND III SUBUNIT ABC4, ABC10-ALPHA, RPB12 |
| 2 | B, Q (2, M) | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA49 | polymer | 415 | 46721.7 | 2 | UniProt (Q01080) Pfam (PF06870) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | A49, DNA-DIRECTED RNA POLYMERASE I 49 KDA POLYPEPTIDE |
| 3 | C, R (3, N) | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA34 | polymer | 233 | 26933.5 | 2 | UniProt (P47006) Pfam (PF08208) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | A34, DNA-DIRECTED DNA-DEPENDENT RNA POLYMERASE 34.5 KDA POLYPEPTIDE, A34.5, A34.5 |
| 4 | D, K, S, Z (4, G, O, V) | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA43 | polymer | 326 | 36264.9 | 4 | UniProt (P46669) Pfam (PF03876) Pfam (PF17875) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | A43, DNA-DIRECTED DNA-DEPENDENT RNA POLYMERASE 36 KDA POLYPEPTIDE, A43 |
| 5 | E, T (A, P) | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA190 | polymer | 1664 | 186677.0 | 2 | UniProt (P10964) Pfam (PF04998) Pfam (PF04997) Pfam (PF00623) Pfam (PF04983) Pfam (PF05000) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | A190, DNA-DIRECTED RNA POLYMERASE I 190 KDA POLYPEPTIDE, DNA-DIRECTED RNA POLYMERASE I LARGEST SUBUNIT |
| 6 | F, U (B, Q) | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA135 | polymer | 1203 | 135910.3 | 2 | UniProt (P22138) Pfam (PF04563) Pfam (PF04561) Pfam (PF04565) Pfam (PF06883) Pfam (PF00562) Pfam (PF04560) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | DNA-DIRECTED RNA POLYMERASE I 135 KDA POLYPEPTIDE, A135, DNA-DIRECTED RNA POLYMERASE I POLYPEPTIDE 2, RNA POLYMERASE I SUBUNIT 2, A135 |
| 7 | G, V (C, R) | DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC1 | polymer | 335 | 37732.6 | 2 | UniProt (P07703) Pfam (PF01193) Pfam (PF01000) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I AND III SUBUNIT AC1, C37, DNA-DIRECTED RN A POLYMERASES I AND III 40 KDA POLYPEPTIDE, AC40, C40, AC40 |
| 8 | H, W (D, S) | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA14 | polymer | 137 | 14599.1 | 2 | UniProt (P50106) Pfam (PF08203) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | A14, DNA-DIRECTED RNA POLYMERASE I 14 KDA POLYPEPTIDE, A14 |
| 9 | I, X (E, T) | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 1 | polymer | 215 | 25117.1 | 2 | UniProt (P20434) Pfam (PF03871) Pfam (PF01191) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I, II, AND III SUBUNIT ABC1, ABC27, DNA-DIRECTED RNA POLYMERASES I\,II\,AND III 27 KDA POLYPEPTIDE, RPB5 |
| 10 | J, Y (F, U) | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 2 | polymer | 155 | 17931.8 | 2 | UniProt (P20435) Pfam (PF01192) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I\,II\,AND III SUBUNIT ABC2, ABC23, DNA-DIRECTED RNA POLYMERASES I\,II\,AND III 23 KDA POLYPEPTIDE, RPB6 |
| 11 | AA, L (H, W) | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 3 | polymer | 146 | 16525.4 | 2 | UniProt (P20436) Pfam (PF03870) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I\,II\,AND III SUBUNIT ABC3, ABC14.4, ABC14.5, DNA-DIRECTED RNA POLYMERASES I\,II\,AND III 14.5 KDA POLYPEPTIDE, RPB8 |
| 12 | BA, M (I, X) | DNA-DIRECTED RNA POLYMERASE I SUBUNIT RPA12 | polymer | 125 | 13676.6 | 2 | UniProt (P32529) Pfam (PF02150) Pfam (PF01096) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | A12, A12.2, DNA-DIRECTED RNA POLYMERASE I 13.7 KDA POLYPEPTIDE, A12.2 |
| 13 | CA, N (J, Y) | DNA-DIRECTED RNA POLYMERASES I, II, AND III SUBUNIT RPABC 5 | polymer | 70 | 8290.7 | 2 | UniProt (P22139) Pfam (PF01194) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I\,II\,AND III SUBUNIT ABC5, ABC10-BETA, ABC8, DNA-DIRECTED RNA POLYMERASES I\,II\,AND III 8.3 KDA POLYPEPTIDE, RPB10 |
| 14 | DA, O (K, Z) | DNA-DIRECTED RNA POLYMERASES I AND III SUBUNIT RPAC2 | polymer | 142 | 16167.9 | 2 | UniProt (P28000) Pfam (PF13656) | SACCHAROMYCES CEREVISIAE (BAKER'S YEAST) | RNA POLYMERASES I AND III SUBUNIT AC2, DNA-DIRECTED R NA POLYMERASES I AND III 16 KDA POLYPEPTIDE, RPA19, AC19 |
| 15 | EA, FA, GA, IA, JA... (1, A, B, I, J...) | ZINC ION | non-polymer | 65.4 | 14 | Chemie (ZN) | |||
| 16 | HA, PA (B, Q) | SULFATE ION | non-polymer | 96.1 | 2 | Chemie (SO4) | |||
| 17 | AB, BB, CB, DB, EB... (F, G, H, I, N...) | water | water | 18.0 | 262 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 30 |
| Total formula weight | 1253086.8 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 1107.9 | |
| All* | Total formula weight | 1254194.6 |
