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4C2M

Structure of RNA polymerase I at 2.8 A resolution

Functional Information from GO Data
ChainGOidnamespacecontents
10000428cellular_componentDNA-directed RNA polymerase complex
10001054molecular_functionRNA polymerase I activity
10001055molecular_functionRNA polymerase II activity
10001056molecular_functionRNA polymerase III activity
10001172biological_processRNA-templated transcription
10003677molecular_functionDNA binding
10003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
10003968molecular_functionRNA-dependent RNA polymerase activity
10005634cellular_componentnucleus
10005654cellular_componentnucleoplasm
10005665cellular_componentRNA polymerase II, core complex
10005666cellular_componentRNA polymerase III complex
10005730cellular_componentnucleolus
10005736cellular_componentRNA polymerase I complex
10005737cellular_componentcytoplasm
10005777cellular_componentperoxisome
10006351biological_processDNA-templated transcription
10006360biological_processtranscription by RNA polymerase I
10006361biological_processtranscription initiation at RNA polymerase I promoter
10006362biological_processtranscription elongation by RNA polymerase I
10006363biological_processtermination of RNA polymerase I transcription
10006366biological_processtranscription by RNA polymerase II
10006367biological_processtranscription initiation at RNA polymerase II promoter
10006368biological_processtranscription elongation by RNA polymerase II
10006383biological_processtranscription by RNA polymerase III
10006384biological_processtranscription initiation at RNA polymerase III promoter
10006386biological_processtermination of RNA polymerase III transcription
10008270molecular_functionzinc ion binding
10042254biological_processribosome biogenesis
10042790biological_processnucleolar large rRNA transcription by RNA polymerase I
10042797biological_processtRNA transcription by RNA polymerase III
10046872molecular_functionmetal ion binding
20000428cellular_componentDNA-directed RNA polymerase complex
20001054molecular_functionRNA polymerase I activity
20001188biological_processRNA polymerase I preinitiation complex assembly
20003677molecular_functionDNA binding
20005634cellular_componentnucleus
20005730cellular_componentnucleolus
20005736cellular_componentRNA polymerase I complex
20006351biological_processDNA-templated transcription
20006360biological_processtranscription by RNA polymerase I
20006361biological_processtranscription initiation at RNA polymerase I promoter
20006362biological_processtranscription elongation by RNA polymerase I
20006363biological_processtermination of RNA polymerase I transcription
20008361biological_processregulation of cell size
20016779molecular_functionnucleotidyltransferase activity
20042254biological_processribosome biogenesis
20042790biological_processnucleolar large rRNA transcription by RNA polymerase I
30000428cellular_componentDNA-directed RNA polymerase complex
30001054molecular_functionRNA polymerase I activity
30005634cellular_componentnucleus
30005730cellular_componentnucleolus
30005736cellular_componentRNA polymerase I complex
30006360biological_processtranscription by RNA polymerase I
30006361biological_processtranscription initiation at RNA polymerase I promoter
30006362biological_processtranscription elongation by RNA polymerase I
30006363biological_processtermination of RNA polymerase I transcription
30042254biological_processribosome biogenesis
30042790biological_processnucleolar large rRNA transcription by RNA polymerase I
40000428cellular_componentDNA-directed RNA polymerase complex
40001054molecular_functionRNA polymerase I activity
40005515molecular_functionprotein binding
40005634cellular_componentnucleus
40005730cellular_componentnucleolus
40005736cellular_componentRNA polymerase I complex
40006351biological_processDNA-templated transcription
40006352biological_processDNA-templated transcription initiation
40006360biological_processtranscription by RNA polymerase I
40006361biological_processtranscription initiation at RNA polymerase I promoter
40006362biological_processtranscription elongation by RNA polymerase I
40006363biological_processtermination of RNA polymerase I transcription
40042254biological_processribosome biogenesis
40042790biological_processnucleolar large rRNA transcription by RNA polymerase I
40055029cellular_componentnuclear DNA-directed RNA polymerase complex
A0000428cellular_componentDNA-directed RNA polymerase complex
A0001054molecular_functionRNA polymerase I activity
A0003677molecular_functionDNA binding
A0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005730cellular_componentnucleolus
A0005736cellular_componentRNA polymerase I complex
A0006351biological_processDNA-templated transcription
A0006360biological_processtranscription by RNA polymerase I
A0006361biological_processtranscription initiation at RNA polymerase I promoter
A0006362biological_processtranscription elongation by RNA polymerase I
A0006363biological_processtermination of RNA polymerase I transcription
A0008270molecular_functionzinc ion binding
A0016779molecular_functionnucleotidyltransferase activity
A0034062molecular_function5'-3' RNA polymerase activity
A0042254biological_processribosome biogenesis
A0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
A0046872molecular_functionmetal ion binding
A1990841molecular_functionpromoter-specific chromatin binding
B0000428cellular_componentDNA-directed RNA polymerase complex
B0001054molecular_functionRNA polymerase I activity
B0003677molecular_functionDNA binding
B0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
B0005515molecular_functionprotein binding
B0005634cellular_componentnucleus
B0005730cellular_componentnucleolus
B0005736cellular_componentRNA polymerase I complex
B0006351biological_processDNA-templated transcription
B0006360biological_processtranscription by RNA polymerase I
B0006361biological_processtranscription initiation at RNA polymerase I promoter
B0006362biological_processtranscription elongation by RNA polymerase I
B0006363biological_processtermination of RNA polymerase I transcription
B0008270molecular_functionzinc ion binding
B0016779molecular_functionnucleotidyltransferase activity
B0032549molecular_functionribonucleoside binding
B0034062molecular_function5'-3' RNA polymerase activity
B0042254biological_processribosome biogenesis
B0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
B0046872molecular_functionmetal ion binding
C0000428cellular_componentDNA-directed RNA polymerase complex
C0001054molecular_functionRNA polymerase I activity
C0001056molecular_functionRNA polymerase III activity
C0003677molecular_functionDNA binding
C0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
C0005515molecular_functionprotein binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005666cellular_componentRNA polymerase III complex
C0005730cellular_componentnucleolus
C0005736cellular_componentRNA polymerase I complex
C0006351biological_processDNA-templated transcription
C0006360biological_processtranscription by RNA polymerase I
C0006361biological_processtranscription initiation at RNA polymerase I promoter
C0006362biological_processtranscription elongation by RNA polymerase I
C0006363biological_processtermination of RNA polymerase I transcription
C0006383biological_processtranscription by RNA polymerase III
C0006384biological_processtranscription initiation at RNA polymerase III promoter
C0006386biological_processtermination of RNA polymerase III transcription
C0042254biological_processribosome biogenesis
C0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
C0042797biological_processtRNA transcription by RNA polymerase III
C0046983molecular_functionprotein dimerization activity
C0055029cellular_componentnuclear DNA-directed RNA polymerase complex
D0000428cellular_componentDNA-directed RNA polymerase complex
D0001054molecular_functionRNA polymerase I activity
D0005515molecular_functionprotein binding
D0005634cellular_componentnucleus
D0005730cellular_componentnucleolus
D0005736cellular_componentRNA polymerase I complex
D0006360biological_processtranscription by RNA polymerase I
D0006361biological_processtranscription initiation at RNA polymerase I promoter
D0006362biological_processtranscription elongation by RNA polymerase I
D0006363biological_processtermination of RNA polymerase I transcription
D0008361biological_processregulation of cell size
D0042254biological_processribosome biogenesis
D0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
E0000428cellular_componentDNA-directed RNA polymerase complex
E0001054molecular_functionRNA polymerase I activity
E0001055molecular_functionRNA polymerase II activity
E0001056molecular_functionRNA polymerase III activity
E0001172biological_processRNA-templated transcription
E0003677molecular_functionDNA binding
E0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
E0003968molecular_functionRNA-dependent RNA polymerase activity
E0005515molecular_functionprotein binding
E0005634cellular_componentnucleus
E0005654cellular_componentnucleoplasm
E0005665cellular_componentRNA polymerase II, core complex
E0005666cellular_componentRNA polymerase III complex
E0005736cellular_componentRNA polymerase I complex
E0006351biological_processDNA-templated transcription
E0006360biological_processtranscription by RNA polymerase I
E0006361biological_processtranscription initiation at RNA polymerase I promoter
E0006362biological_processtranscription elongation by RNA polymerase I
E0006363biological_processtermination of RNA polymerase I transcription
E0006366biological_processtranscription by RNA polymerase II
E0006367biological_processtranscription initiation at RNA polymerase II promoter
E0006368biological_processtranscription elongation by RNA polymerase II
E0006383biological_processtranscription by RNA polymerase III
E0006384biological_processtranscription initiation at RNA polymerase III promoter
E0006386biological_processtermination of RNA polymerase III transcription
E0042254biological_processribosome biogenesis
E0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
E0042797biological_processtRNA transcription by RNA polymerase III
F0000428cellular_componentDNA-directed RNA polymerase complex
F0001054molecular_functionRNA polymerase I activity
F0001055molecular_functionRNA polymerase II activity
F0001056molecular_functionRNA polymerase III activity
F0001172biological_processRNA-templated transcription
F0003677molecular_functionDNA binding
F0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
F0003968molecular_functionRNA-dependent RNA polymerase activity
F0005515molecular_functionprotein binding
F0005634cellular_componentnucleus
F0005654cellular_componentnucleoplasm
F0005665cellular_componentRNA polymerase II, core complex
F0005666cellular_componentRNA polymerase III complex
F0005736cellular_componentRNA polymerase I complex
F0005737cellular_componentcytoplasm
F0006351biological_processDNA-templated transcription
F0006360biological_processtranscription by RNA polymerase I
F0006361biological_processtranscription initiation at RNA polymerase I promoter
F0006362biological_processtranscription elongation by RNA polymerase I
F0006363biological_processtermination of RNA polymerase I transcription
F0006366biological_processtranscription by RNA polymerase II
F0006367biological_processtranscription initiation at RNA polymerase II promoter
F0006368biological_processtranscription elongation by RNA polymerase II
F0006383biological_processtranscription by RNA polymerase III
F0006384biological_processtranscription initiation at RNA polymerase III promoter
F0006386biological_processtermination of RNA polymerase III transcription
F0042254biological_processribosome biogenesis
F0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
F0042797biological_processtRNA transcription by RNA polymerase III
G0000428cellular_componentDNA-directed RNA polymerase complex
G0001054molecular_functionRNA polymerase I activity
G0005515molecular_functionprotein binding
G0005634cellular_componentnucleus
G0005730cellular_componentnucleolus
G0005736cellular_componentRNA polymerase I complex
G0006351biological_processDNA-templated transcription
G0006352biological_processDNA-templated transcription initiation
G0006360biological_processtranscription by RNA polymerase I
G0006361biological_processtranscription initiation at RNA polymerase I promoter
G0006362biological_processtranscription elongation by RNA polymerase I
G0006363biological_processtermination of RNA polymerase I transcription
G0042254biological_processribosome biogenesis
G0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
G0055029cellular_componentnuclear DNA-directed RNA polymerase complex
H0000428cellular_componentDNA-directed RNA polymerase complex
H0001054molecular_functionRNA polymerase I activity
H0001055molecular_functionRNA polymerase II activity
H0001056molecular_functionRNA polymerase III activity
H0001172biological_processRNA-templated transcription
H0003677molecular_functionDNA binding
H0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
H0003968molecular_functionRNA-dependent RNA polymerase activity
H0005515molecular_functionprotein binding
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0005665cellular_componentRNA polymerase II, core complex
H0005666cellular_componentRNA polymerase III complex
H0005736cellular_componentRNA polymerase I complex
H0006351biological_processDNA-templated transcription
H0006360biological_processtranscription by RNA polymerase I
H0006361biological_processtranscription initiation at RNA polymerase I promoter
H0006362biological_processtranscription elongation by RNA polymerase I
H0006363biological_processtermination of RNA polymerase I transcription
H0006366biological_processtranscription by RNA polymerase II
H0006367biological_processtranscription initiation at RNA polymerase II promoter
H0006368biological_processtranscription elongation by RNA polymerase II
H0006383biological_processtranscription by RNA polymerase III
H0006384biological_processtranscription initiation at RNA polymerase III promoter
H0006386biological_processtermination of RNA polymerase III transcription
H0042254biological_processribosome biogenesis
H0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
H0042797biological_processtRNA transcription by RNA polymerase III
I0000122biological_processnegative regulation of transcription by RNA polymerase II
I0000428cellular_componentDNA-directed RNA polymerase complex
I0001054molecular_functionRNA polymerase I activity
I0003676molecular_functionnucleic acid binding
I0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
I0005634cellular_componentnucleus
I0005730cellular_componentnucleolus
I0005736cellular_componentRNA polymerase I complex
I0006351biological_processDNA-templated transcription
I0006360biological_processtranscription by RNA polymerase I
I0006361biological_processtranscription initiation at RNA polymerase I promoter
I0006362biological_processtranscription elongation by RNA polymerase I
I0006363biological_processtermination of RNA polymerase I transcription
I0008270molecular_functionzinc ion binding
I0042254biological_processribosome biogenesis
I0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
I0046872molecular_functionmetal ion binding
I0055029cellular_componentnuclear DNA-directed RNA polymerase complex
I0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
J0000428cellular_componentDNA-directed RNA polymerase complex
J0001054molecular_functionRNA polymerase I activity
J0001055molecular_functionRNA polymerase II activity
J0001056molecular_functionRNA polymerase III activity
J0001172biological_processRNA-templated transcription
J0003677molecular_functionDNA binding
J0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
J0003968molecular_functionRNA-dependent RNA polymerase activity
J0005515molecular_functionprotein binding
J0005634cellular_componentnucleus
J0005654cellular_componentnucleoplasm
J0005665cellular_componentRNA polymerase II, core complex
J0005666cellular_componentRNA polymerase III complex
J0005730cellular_componentnucleolus
J0005736cellular_componentRNA polymerase I complex
J0006351biological_processDNA-templated transcription
J0006360biological_processtranscription by RNA polymerase I
J0006361biological_processtranscription initiation at RNA polymerase I promoter
J0006362biological_processtranscription elongation by RNA polymerase I
J0006363biological_processtermination of RNA polymerase I transcription
J0006366biological_processtranscription by RNA polymerase II
J0006367biological_processtranscription initiation at RNA polymerase II promoter
J0006368biological_processtranscription elongation by RNA polymerase II
J0006383biological_processtranscription by RNA polymerase III
J0006384biological_processtranscription initiation at RNA polymerase III promoter
J0006386biological_processtermination of RNA polymerase III transcription
J0008270molecular_functionzinc ion binding
J0042254biological_processribosome biogenesis
J0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
J0042797biological_processtRNA transcription by RNA polymerase III
J0046872molecular_functionmetal ion binding
K0000428cellular_componentDNA-directed RNA polymerase complex
K0001054molecular_functionRNA polymerase I activity
K0001056molecular_functionRNA polymerase III activity
K0003677molecular_functionDNA binding
K0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
K0005515molecular_functionprotein binding
K0005634cellular_componentnucleus
K0005654cellular_componentnucleoplasm
K0005666cellular_componentRNA polymerase III complex
K0005730cellular_componentnucleolus
K0005736cellular_componentRNA polymerase I complex
K0006351biological_processDNA-templated transcription
K0006360biological_processtranscription by RNA polymerase I
K0006361biological_processtranscription initiation at RNA polymerase I promoter
K0006362biological_processtranscription elongation by RNA polymerase I
K0006363biological_processtermination of RNA polymerase I transcription
K0006383biological_processtranscription by RNA polymerase III
K0006384biological_processtranscription initiation at RNA polymerase III promoter
K0006386biological_processtermination of RNA polymerase III transcription
K0042254biological_processribosome biogenesis
K0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
K0042797biological_processtRNA transcription by RNA polymerase III
K0046983molecular_functionprotein dimerization activity
K0055029cellular_componentnuclear DNA-directed RNA polymerase complex
L0000428cellular_componentDNA-directed RNA polymerase complex
L0001054molecular_functionRNA polymerase I activity
L0001055molecular_functionRNA polymerase II activity
L0001056molecular_functionRNA polymerase III activity
L0001172biological_processRNA-templated transcription
L0003677molecular_functionDNA binding
L0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
L0003968molecular_functionRNA-dependent RNA polymerase activity
L0005634cellular_componentnucleus
L0005654cellular_componentnucleoplasm
L0005665cellular_componentRNA polymerase II, core complex
L0005666cellular_componentRNA polymerase III complex
L0005730cellular_componentnucleolus
L0005736cellular_componentRNA polymerase I complex
L0005737cellular_componentcytoplasm
L0005777cellular_componentperoxisome
L0006351biological_processDNA-templated transcription
L0006360biological_processtranscription by RNA polymerase I
L0006361biological_processtranscription initiation at RNA polymerase I promoter
L0006362biological_processtranscription elongation by RNA polymerase I
L0006363biological_processtermination of RNA polymerase I transcription
L0006366biological_processtranscription by RNA polymerase II
L0006367biological_processtranscription initiation at RNA polymerase II promoter
L0006368biological_processtranscription elongation by RNA polymerase II
L0006383biological_processtranscription by RNA polymerase III
L0006384biological_processtranscription initiation at RNA polymerase III promoter
L0006386biological_processtermination of RNA polymerase III transcription
L0008270molecular_functionzinc ion binding
L0042254biological_processribosome biogenesis
L0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
L0042797biological_processtRNA transcription by RNA polymerase III
L0046872molecular_functionmetal ion binding
M0000428cellular_componentDNA-directed RNA polymerase complex
M0001054molecular_functionRNA polymerase I activity
M0001188biological_processRNA polymerase I preinitiation complex assembly
M0003677molecular_functionDNA binding
M0005634cellular_componentnucleus
M0005730cellular_componentnucleolus
M0005736cellular_componentRNA polymerase I complex
M0006351biological_processDNA-templated transcription
M0006360biological_processtranscription by RNA polymerase I
M0006361biological_processtranscription initiation at RNA polymerase I promoter
M0006362biological_processtranscription elongation by RNA polymerase I
M0006363biological_processtermination of RNA polymerase I transcription
M0008361biological_processregulation of cell size
M0016779molecular_functionnucleotidyltransferase activity
M0042254biological_processribosome biogenesis
M0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
N0000428cellular_componentDNA-directed RNA polymerase complex
N0001054molecular_functionRNA polymerase I activity
N0005634cellular_componentnucleus
N0005730cellular_componentnucleolus
N0005736cellular_componentRNA polymerase I complex
N0006360biological_processtranscription by RNA polymerase I
N0006361biological_processtranscription initiation at RNA polymerase I promoter
N0006362biological_processtranscription elongation by RNA polymerase I
N0006363biological_processtermination of RNA polymerase I transcription
N0042254biological_processribosome biogenesis
N0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
O0000428cellular_componentDNA-directed RNA polymerase complex
O0001054molecular_functionRNA polymerase I activity
O0005515molecular_functionprotein binding
O0005634cellular_componentnucleus
O0005730cellular_componentnucleolus
O0005736cellular_componentRNA polymerase I complex
O0006351biological_processDNA-templated transcription
O0006352biological_processDNA-templated transcription initiation
O0006360biological_processtranscription by RNA polymerase I
O0006361biological_processtranscription initiation at RNA polymerase I promoter
O0006362biological_processtranscription elongation by RNA polymerase I
O0006363biological_processtermination of RNA polymerase I transcription
O0042254biological_processribosome biogenesis
O0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
O0055029cellular_componentnuclear DNA-directed RNA polymerase complex
P0000428cellular_componentDNA-directed RNA polymerase complex
P0001054molecular_functionRNA polymerase I activity
P0003677molecular_functionDNA binding
P0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
P0005515molecular_functionprotein binding
P0005634cellular_componentnucleus
P0005730cellular_componentnucleolus
P0005736cellular_componentRNA polymerase I complex
P0006351biological_processDNA-templated transcription
P0006360biological_processtranscription by RNA polymerase I
P0006361biological_processtranscription initiation at RNA polymerase I promoter
P0006362biological_processtranscription elongation by RNA polymerase I
P0006363biological_processtermination of RNA polymerase I transcription
P0008270molecular_functionzinc ion binding
P0016779molecular_functionnucleotidyltransferase activity
P0034062molecular_function5'-3' RNA polymerase activity
P0042254biological_processribosome biogenesis
P0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
P0046872molecular_functionmetal ion binding
P1990841molecular_functionpromoter-specific chromatin binding
Q0000428cellular_componentDNA-directed RNA polymerase complex
Q0001054molecular_functionRNA polymerase I activity
Q0003677molecular_functionDNA binding
Q0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
Q0005515molecular_functionprotein binding
Q0005634cellular_componentnucleus
Q0005730cellular_componentnucleolus
Q0005736cellular_componentRNA polymerase I complex
Q0006351biological_processDNA-templated transcription
Q0006360biological_processtranscription by RNA polymerase I
Q0006361biological_processtranscription initiation at RNA polymerase I promoter
Q0006362biological_processtranscription elongation by RNA polymerase I
Q0006363biological_processtermination of RNA polymerase I transcription
Q0008270molecular_functionzinc ion binding
Q0016779molecular_functionnucleotidyltransferase activity
Q0032549molecular_functionribonucleoside binding
Q0034062molecular_function5'-3' RNA polymerase activity
Q0042254biological_processribosome biogenesis
Q0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
Q0046872molecular_functionmetal ion binding
R0000428cellular_componentDNA-directed RNA polymerase complex
R0001054molecular_functionRNA polymerase I activity
R0001056molecular_functionRNA polymerase III activity
R0003677molecular_functionDNA binding
R0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
R0005515molecular_functionprotein binding
R0005634cellular_componentnucleus
R0005654cellular_componentnucleoplasm
R0005666cellular_componentRNA polymerase III complex
R0005730cellular_componentnucleolus
R0005736cellular_componentRNA polymerase I complex
R0006351biological_processDNA-templated transcription
R0006360biological_processtranscription by RNA polymerase I
R0006361biological_processtranscription initiation at RNA polymerase I promoter
R0006362biological_processtranscription elongation by RNA polymerase I
R0006363biological_processtermination of RNA polymerase I transcription
R0006383biological_processtranscription by RNA polymerase III
R0006384biological_processtranscription initiation at RNA polymerase III promoter
R0006386biological_processtermination of RNA polymerase III transcription
R0042254biological_processribosome biogenesis
R0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
R0042797biological_processtRNA transcription by RNA polymerase III
R0046983molecular_functionprotein dimerization activity
R0055029cellular_componentnuclear DNA-directed RNA polymerase complex
S0000428cellular_componentDNA-directed RNA polymerase complex
S0001054molecular_functionRNA polymerase I activity
S0005515molecular_functionprotein binding
S0005634cellular_componentnucleus
S0005730cellular_componentnucleolus
S0005736cellular_componentRNA polymerase I complex
S0006360biological_processtranscription by RNA polymerase I
S0006361biological_processtranscription initiation at RNA polymerase I promoter
S0006362biological_processtranscription elongation by RNA polymerase I
S0006363biological_processtermination of RNA polymerase I transcription
S0008361biological_processregulation of cell size
S0042254biological_processribosome biogenesis
S0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
T0000428cellular_componentDNA-directed RNA polymerase complex
T0001054molecular_functionRNA polymerase I activity
T0001055molecular_functionRNA polymerase II activity
T0001056molecular_functionRNA polymerase III activity
T0001172biological_processRNA-templated transcription
T0003677molecular_functionDNA binding
T0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
T0003968molecular_functionRNA-dependent RNA polymerase activity
T0005515molecular_functionprotein binding
T0005634cellular_componentnucleus
T0005654cellular_componentnucleoplasm
T0005665cellular_componentRNA polymerase II, core complex
T0005666cellular_componentRNA polymerase III complex
T0005736cellular_componentRNA polymerase I complex
T0006351biological_processDNA-templated transcription
T0006360biological_processtranscription by RNA polymerase I
T0006361biological_processtranscription initiation at RNA polymerase I promoter
T0006362biological_processtranscription elongation by RNA polymerase I
T0006363biological_processtermination of RNA polymerase I transcription
T0006366biological_processtranscription by RNA polymerase II
T0006367biological_processtranscription initiation at RNA polymerase II promoter
T0006368biological_processtranscription elongation by RNA polymerase II
T0006383biological_processtranscription by RNA polymerase III
T0006384biological_processtranscription initiation at RNA polymerase III promoter
T0006386biological_processtermination of RNA polymerase III transcription
T0042254biological_processribosome biogenesis
T0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
T0042797biological_processtRNA transcription by RNA polymerase III
U0000428cellular_componentDNA-directed RNA polymerase complex
U0001054molecular_functionRNA polymerase I activity
U0001055molecular_functionRNA polymerase II activity
U0001056molecular_functionRNA polymerase III activity
U0001172biological_processRNA-templated transcription
U0003677molecular_functionDNA binding
U0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
U0003968molecular_functionRNA-dependent RNA polymerase activity
U0005515molecular_functionprotein binding
U0005634cellular_componentnucleus
U0005654cellular_componentnucleoplasm
U0005665cellular_componentRNA polymerase II, core complex
U0005666cellular_componentRNA polymerase III complex
U0005736cellular_componentRNA polymerase I complex
U0005737cellular_componentcytoplasm
U0006351biological_processDNA-templated transcription
U0006360biological_processtranscription by RNA polymerase I
U0006361biological_processtranscription initiation at RNA polymerase I promoter
U0006362biological_processtranscription elongation by RNA polymerase I
U0006363biological_processtermination of RNA polymerase I transcription
U0006366biological_processtranscription by RNA polymerase II
U0006367biological_processtranscription initiation at RNA polymerase II promoter
U0006368biological_processtranscription elongation by RNA polymerase II
U0006383biological_processtranscription by RNA polymerase III
U0006384biological_processtranscription initiation at RNA polymerase III promoter
U0006386biological_processtermination of RNA polymerase III transcription
U0042254biological_processribosome biogenesis
U0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
U0042797biological_processtRNA transcription by RNA polymerase III
V0000428cellular_componentDNA-directed RNA polymerase complex
V0001054molecular_functionRNA polymerase I activity
V0005515molecular_functionprotein binding
V0005634cellular_componentnucleus
V0005730cellular_componentnucleolus
V0005736cellular_componentRNA polymerase I complex
V0006351biological_processDNA-templated transcription
V0006352biological_processDNA-templated transcription initiation
V0006360biological_processtranscription by RNA polymerase I
V0006361biological_processtranscription initiation at RNA polymerase I promoter
V0006362biological_processtranscription elongation by RNA polymerase I
V0006363biological_processtermination of RNA polymerase I transcription
V0042254biological_processribosome biogenesis
V0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
V0055029cellular_componentnuclear DNA-directed RNA polymerase complex
W0000428cellular_componentDNA-directed RNA polymerase complex
W0001054molecular_functionRNA polymerase I activity
W0001055molecular_functionRNA polymerase II activity
W0001056molecular_functionRNA polymerase III activity
W0001172biological_processRNA-templated transcription
W0003677molecular_functionDNA binding
W0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
W0003968molecular_functionRNA-dependent RNA polymerase activity
W0005515molecular_functionprotein binding
W0005634cellular_componentnucleus
W0005654cellular_componentnucleoplasm
W0005665cellular_componentRNA polymerase II, core complex
W0005666cellular_componentRNA polymerase III complex
W0005736cellular_componentRNA polymerase I complex
W0006351biological_processDNA-templated transcription
W0006360biological_processtranscription by RNA polymerase I
W0006361biological_processtranscription initiation at RNA polymerase I promoter
W0006362biological_processtranscription elongation by RNA polymerase I
W0006363biological_processtermination of RNA polymerase I transcription
W0006366biological_processtranscription by RNA polymerase II
W0006367biological_processtranscription initiation at RNA polymerase II promoter
W0006368biological_processtranscription elongation by RNA polymerase II
W0006383biological_processtranscription by RNA polymerase III
W0006384biological_processtranscription initiation at RNA polymerase III promoter
W0006386biological_processtermination of RNA polymerase III transcription
W0042254biological_processribosome biogenesis
W0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
W0042797biological_processtRNA transcription by RNA polymerase III
X0000122biological_processnegative regulation of transcription by RNA polymerase II
X0000428cellular_componentDNA-directed RNA polymerase complex
X0001054molecular_functionRNA polymerase I activity
X0003676molecular_functionnucleic acid binding
X0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
X0005634cellular_componentnucleus
X0005730cellular_componentnucleolus
X0005736cellular_componentRNA polymerase I complex
X0006351biological_processDNA-templated transcription
X0006360biological_processtranscription by RNA polymerase I
X0006361biological_processtranscription initiation at RNA polymerase I promoter
X0006362biological_processtranscription elongation by RNA polymerase I
X0006363biological_processtermination of RNA polymerase I transcription
X0008270molecular_functionzinc ion binding
X0042254biological_processribosome biogenesis
X0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
X0046872molecular_functionmetal ion binding
X0055029cellular_componentnuclear DNA-directed RNA polymerase complex
X0061629molecular_functionRNA polymerase II-specific DNA-binding transcription factor binding
Y0000428cellular_componentDNA-directed RNA polymerase complex
Y0001054molecular_functionRNA polymerase I activity
Y0001055molecular_functionRNA polymerase II activity
Y0001056molecular_functionRNA polymerase III activity
Y0001172biological_processRNA-templated transcription
Y0003677molecular_functionDNA binding
Y0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
Y0003968molecular_functionRNA-dependent RNA polymerase activity
Y0005515molecular_functionprotein binding
Y0005634cellular_componentnucleus
Y0005654cellular_componentnucleoplasm
Y0005665cellular_componentRNA polymerase II, core complex
Y0005666cellular_componentRNA polymerase III complex
Y0005730cellular_componentnucleolus
Y0005736cellular_componentRNA polymerase I complex
Y0006351biological_processDNA-templated transcription
Y0006360biological_processtranscription by RNA polymerase I
Y0006361biological_processtranscription initiation at RNA polymerase I promoter
Y0006362biological_processtranscription elongation by RNA polymerase I
Y0006363biological_processtermination of RNA polymerase I transcription
Y0006366biological_processtranscription by RNA polymerase II
Y0006367biological_processtranscription initiation at RNA polymerase II promoter
Y0006368biological_processtranscription elongation by RNA polymerase II
Y0006383biological_processtranscription by RNA polymerase III
Y0006384biological_processtranscription initiation at RNA polymerase III promoter
Y0006386biological_processtermination of RNA polymerase III transcription
Y0008270molecular_functionzinc ion binding
Y0042254biological_processribosome biogenesis
Y0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
Y0042797biological_processtRNA transcription by RNA polymerase III
Y0046872molecular_functionmetal ion binding
Z0000428cellular_componentDNA-directed RNA polymerase complex
Z0001054molecular_functionRNA polymerase I activity
Z0001056molecular_functionRNA polymerase III activity
Z0003677molecular_functionDNA binding
Z0003899molecular_functionDNA-directed 5'-3' RNA polymerase activity
Z0005515molecular_functionprotein binding
Z0005634cellular_componentnucleus
Z0005654cellular_componentnucleoplasm
Z0005666cellular_componentRNA polymerase III complex
Z0005730cellular_componentnucleolus
Z0005736cellular_componentRNA polymerase I complex
Z0006351biological_processDNA-templated transcription
Z0006360biological_processtranscription by RNA polymerase I
Z0006361biological_processtranscription initiation at RNA polymerase I promoter
Z0006362biological_processtranscription elongation by RNA polymerase I
Z0006363biological_processtermination of RNA polymerase I transcription
Z0006383biological_processtranscription by RNA polymerase III
Z0006384biological_processtranscription initiation at RNA polymerase III promoter
Z0006386biological_processtermination of RNA polymerase III transcription
Z0042254biological_processribosome biogenesis
Z0042790biological_processnucleolar large rRNA transcription by RNA polymerase I
Z0042797biological_processtRNA transcription by RNA polymerase III
Z0046983molecular_functionprotein dimerization activity
Z0055029cellular_componentnuclear DNA-directed RNA polymerase complex
Functional Information from PDB Data
site_idAC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN 1 3001
ChainResidue
1CYS31
1CYS34
1CYS48
1CYS51

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 3001
ChainResidue
ACYS62
ACYS65
ACYS72
AHIS75

site_idAC3
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN A 3002
ChainResidue
ACYS105
ACYS233
ACYS236
ACYS102

site_idAC4
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN B 3001
ChainResidue
BCYS1104
BCYS1107
BCYS1128
BCYS1131

site_idAC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN I 3001
ChainResidue
ICYS10
ICYS13
ICYS30
ICYS33

site_idAC6
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN I 3002
ChainResidue
ICYS86
ICYS89
ICYS114
ICYS117

site_idAC7
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN J 3001
ChainResidue
JCYS7
JCYS10
JCYS45
JCYS46

site_idAC8
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN L 3001
ChainResidue
LCYS31
LCYS34
LCYS48
LCYS51

site_idAC9
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN P 3001
ChainResidue
PCYS62
PCYS65
PCYS72
PHIS75

site_idBC1
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN P 3002
ChainResidue
PCYS102
PCYS105
PCYS233
PCYS236

site_idBC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN Q 3001
ChainResidue
QCYS1104
QCYS1107
QCYS1128
QCYS1131

site_idBC3
Number of Residues7
DetailsBINDING SITE FOR RESIDUE SO4 B 2204
ChainResidue
BSER498
BARG501
BHIS532
BHIS544
BSER698
BILE699
BLEU700

site_idBC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 Q 2204
ChainResidue
QHIS532
QHIS544
QSER698
QILE699
QLEU700

site_idBC5
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN X 3001
ChainResidue
XCYS10
XCYS13
XCYS30
XCYS33

site_idBC6
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN X 3002
ChainResidue
XCYS86
XCYS89
XCYS114
XCYS117

site_idBC7
Number of Residues4
DetailsBINDING SITE FOR RESIDUE ZN Y 3001
ChainResidue
YCYS7
YCYS10
YCYS45
YCYS46

Functional Information from PROSITE/UniProt
site_idPS00446
Number of Residues41
DetailsRNA_POL_D_30KD RNA polymerases D / 30 to 40 Kd subunits signature. NAFRRimisevpsvAaeyVyffnNtSviqDEvLAhRIGLVP
ChainResidueDetails
CASN65-PRO105

site_idPS00466
Number of Residues36
DetailsZF_TFIIS_1 Zinc finger TFIIS-type signature. CpqCgneemnyhtLQLRSaDEGatvfytCts...CgykF
ChainResidueDetails
XCYS86-PHE121

site_idPS01030
Number of Residues25
DetailsRNA_POL_M_15KD RNA polymerases M / 15 Kd subunits signature. FCLDCGDLLenpnavlgsnve..CsqC
ChainResidueDetails
XPHE9-CYS33

site_idPS01110
Number of Residues14
DetailsRNA_POL_H_23KD RNA polymerases H / 23 Kd subunits signature. HELVPKHirLssDE
ChainResidueDetails
EHIS147-GLU160

site_idPS01111
Number of Residues15
DetailsRNA_POL_K_14KD RNA polymerases K / 14 to 18 Kd subunits signature. TkYErARiLGtRAlQ
ChainResidueDetails
FTHR86-GLN100

site_idPS01112
Number of Residues10
DetailsRNA_POL_N_8KD RNA polymerases N / 8 Kd subunits signature. IVPVrCFSCG
ChainResidueDetails
YILE2-GLY11

site_idPS01154
Number of Residues32
DetailsRNA_POL_L_13KD RNA polymerases L / 13 to 16 Kd subunits signature. IveEdHTLgNaLryvImknpdVefcgYsipHP
ChainResidueDetails
ZILE65-PRO96

site_idPS01166
Number of Residues13
DetailsRNA_POL_BETA RNA polymerases beta chain signature. GdKFSSrHGQKGV
ChainResidueDetails
BGLY914-VAL926

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
ChainResidueDetails
KTHR15
PCYS65
PCYS72
PHIS75
PCYS102
PCYS105
PCYS233
PCYS236
ZTHR15
JCYS45
JCYS46
YCYS7
YCYS10
YCYS45
YCYS46
PCYS62

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:17330950, ECO:0007744|PubMed:18407956, ECO:0007744|PubMed:19779198
ChainResidueDetails
KTHR33
ZTHR33
YLYS59
PASP627
PASP629
PASP631
LCYS48
LCYS51

site_idSWS_FT_FI3
Number of Residues4
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047
ChainResidueDetails
KLYS134
ICYS13
ZLYS134
ICYS33
XCYS10
XCYS13
XCYS30
XCYS33

site_idSWS_FT_FI4
Number of Residues8
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00472
ChainResidueDetails
ICYS86
ICYS89
ICYS114
ICYS117
XCYS86
XCYS89
XCYS114
XCYS117

225681

PDB entries from 2024-10-02

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