4C04
Crystal structure of M. musculus protein arginine methyltransferase PRMT6 with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | PROTEIN ARGININE N-METHYLTRANSFERASE 6 | polymer | 382 | 42321.8 | 1 | UniProt (Q6NZB1) Pfam (PF13649) Pfam (PF22528) | MUS MUSCULUS (HOUSE MOUSE) | HISTONE-ARGININE N-METHYLTRANSFERASE PRMT6, |
| 2 | B (A) | SINEFUNGIN | non-polymer | 381.4 | 1 | Chemie (SFG) PubChem (25246236) PubChem (46875078) PubChem (46936257) PubChem (176612030) PubChem (177116271) PubChem (65482) PubChem (70789212) PubChem (93287274) PubChem (70602121) PubChem (12771338) PubChem (92403972) PubChem (93287270) PubChem (93287272) PubChem (93475589) PubChem (456189) PubChem (4065234) PubChem (6917665) PubChem (131971033) PubChem (131972810) PubChem (138626357) PubChem (12771337) PubChem (156562738) PubChem (162866891) PubChem (163339130) PubChem (168280605) | |||
| 3 | C (A) | water | water | 18.0 | 224 | Chemie (HOH) |
Sequence modifications
A: 1 - 378 (UniProt: Q6NZB1)
| PDB | External Database | Details |
|---|---|---|
| Arg -3 | - | expression tag |
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Leu 315 | Phe 315 | variant |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 42321.8 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 381.4 | |
| All* | Total formula weight | 42703.2 |
