4BXO

Architecture and DNA recognition elements of the Fanconi anemia FANCM- FAAP24 complex

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A	FANCONI ANEMIA GROUP M PROTEIN	polymer	254	28772.0	1	UniProt (Q8IYD8) Pfam (PF02732) In PDB	HOMO SAPIENS (HUMAN)	PROTEIN FACM, ATP-DEPENDENT RNA HELICASE FANCM, FANCONI ANE MIA-ASSOCIATED POLYPEPTIDE OF 250 KDA, FAAP250, PROTEIN HEF ORTHOL OG, FANCM
2	B	FANCONI ANEMIA-ASSOCIATED PROTEIN OF 24 KDA	polymer	217	24051.0	1	UniProt (Q9BTP7) Pfam (PF17949) Pfam (PF12826) In PDB	HOMO SAPIENS (HUMAN)	FAAP24
3	H	5'-D(*TP*CP*AP*GP*CP*AP*TP*CP*AP*TP*CP)-3'	polymer	11	3413.2	1		SYNTHETIC CONSTRUCT
4	I	5'-D(*GP*AP*TP*GP*AP*TP*GP*CP*TP*GP*CP)-3'	polymer	11	3293.2	1		SYNTHETIC CONSTRUCT
5	A, B	CALCIUM ION	non-polymer		40.1	4	Chemie (CA)
6		water	water		18.0	100	Chemie (HOH)

Sequence modifications

A: 1798 - 2048 (UniProt: Q8IYD8)

PDB	External Database	Details
Gly 1795	-	expression tag
Ser 1796	-	expression tag
Gly 1797	-	expression tag

B: 1 - 214 (UniProt: Q9BTP7)

PDB	External Database	Details
Gly -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag
Glu 32	Gln 32	conflict

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	59529.3
Non-Polymers*	Number of molecules	4
	Total formula weight	160.3
All*	Total formula weight	59689.7

*Water molecules are not included.