4BXO
Architecture and DNA recognition elements of the Fanconi anemia FANCM- FAAP24 complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | FANCONI ANEMIA GROUP M PROTEIN | polymer | 254 | 28772.0 | 1 | UniProt (Q8IYD8) Pfam (PF02732) | HOMO SAPIENS (HUMAN) | PROTEIN FACM, ATP-DEPENDENT RNA HELICASE FANCM, FANCONI ANE MIA-ASSOCIATED POLYPEPTIDE OF 250 KDA, FAAP250, PROTEIN HEF ORTHOL OG, FANCM |
| 2 | B (B) | FANCONI ANEMIA-ASSOCIATED PROTEIN OF 24 KDA | polymer | 217 | 24051.0 | 1 | UniProt (Q9BTP7) Pfam (PF17949) Pfam (PF12826) | HOMO SAPIENS (HUMAN) | FAAP24 |
| 3 | C (H) | 5'-D(*TP*CP*AP*GP*CP*AP*TP*CP*AP*TP*CP)-3' | polymer | 11 | 3413.2 | 1 | SYNTHETIC CONSTRUCT | ||
| 4 | D (I) | 5'-D(*GP*AP*TP*GP*AP*TP*GP*CP*TP*GP*CP)-3' | polymer | 11 | 3293.2 | 1 | SYNTHETIC CONSTRUCT | ||
| 5 | E, F, G, H (A, B) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 6 | I, J, K, L (A, B, H, I) | water | water | 18.0 | 100 | Chemie (HOH) |
Sequence modifications
A: 1798 - 2048 (UniProt: Q8IYD8)
B: 1 - 214 (UniProt: Q9BTP7)
| PDB | External Database | Details |
|---|---|---|
| Gly 1795 | - | expression tag |
| Ser 1796 | - | expression tag |
| Gly 1797 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Gly -2 | - | expression tag |
| Ser -1 | - | expression tag |
| His 0 | - | expression tag |
| Glu 32 | Gln 32 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 59529.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 160.3 | |
| All* | Total formula weight | 59689.7 |
