4BVU

Structure of Shigella effector OspG in complex with host UbcH5c- Ubiquitin conjugate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	PROTEIN KINASE OSPG	polymer	211	24390.3	1	UniProt (Q99PZ6) Pfam (PF22303)	SHIGELLA FLEXNERI	EFFECTOR PROTEIN OSPG, OSPG
2	B (B)	UBIQUITIN-CONJUGATING ENZYME E2 D3	polymer	147	16690.1	1	UniProt (P61077) Pfam (PF00179)	HOMO SAPIENS (HUMAN)	UBIQUITIN CARRIER PROTEIN D3, UBIQUITIN-CONJUGATING ENZYME E2(17)KB 3, UBIQUITIN-CONJUGATING ENZYME E2-17 KDA 3, UBIQUITIN-PROTEIN LIGASE D3, UBCH5C
3	C (C)	UBIQUITIN	polymer	76	8576.8	1	UniProt (P0CG48) Pfam (PF00240)	HOMO SAPIENS (HUMAN)
4	D, E, F (A, B, C)	water	water		18.0	53	Chemie (HOH)

Sequence modifications

A: 1 - 196 (UniProt: Q99PZ6)

PDB	External Database	Details
Met -14	-	expression tag
Gly -13	-	expression tag
His -12	-	expression tag
His -11	-	expression tag
His -10	-	expression tag
His -9	-	expression tag
His -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
Ser -2	-	expression tag
Ser -1	-	expression tag
Gly 0	-	expression tag

B: 1 - 147 (UniProt: P61077)

PDB	External Database	Details
Ser 85	Cys 85	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	49657.2
All*	Total formula weight	49657.2

*Water molecules are not included.