4BV7
Identification of small molecule inhibitors selective for apo(a) kringles KIV-7, KIV-10 and KV.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | APOLIPOPROTEIN(A) | polymer | 79 | 9156.1 | 1 | UniProt (P08519) Pfam (PF00051) | HOMO SAPIENS (HUMAN) | APOLIPOPROTEIN A, APO(A), LP(A) |
| 2 | B, C (A) | ACETATE ION | non-polymer | 59.0 | 2 | Chemie (ACT) | |||
| 3 | D (A) | 3-(4-piperidyl)propanoic acid | non-polymer | 157.2 | 1 | Chemie (BV7) | |||
| 4 | E (A) | water | water | 18.0 | 93 | Chemie (HOH) |
Sequence modifications
A: 0 - 80 (UniProt: P08519)
| PDB | External Database | Details |
|---|---|---|
| Ala 76 | Asn 4197 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 9156.1 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 275.3 | |
| All* | Total formula weight | 9431.4 |
