4BV4
Structure and allostery in Toll-Spatzle recognition
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (L, M) | PROTEIN SPAETZLE C-106 | polymer | 107 | 11992.5 | 2 | UniProt (P48607) Pfam (PF16077) | DROSOPHILA MELANOGASTER (FRUIT FLY) | PROTEIN SPAETZLE |
| 2 | C (R) | PROTEIN TOLL, VARIABLE LYMPHOCYTE RECEPTOR B CHIMERA | polymer | 446 | 50749.9 | 1 | UniProt (P08953) UniProt (Q4G1L2) Pfam (PF13855) Pfam (PF11921) | DROSOPHILA MELANOGASTER (FRUIT FLY) | |
| 3 | D (A) | alpha-D-mannopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-3)-[beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1397.2 | 1 | In PDB GlyTouCan (G50714RV) | |||
| 4 | E, F, G, H (R) | 2-acetamido-2-deoxy-beta-D-glucopyranose | non-polymer | 221.2 | 4 | Chemie (NAG) | |||
| 5 | I, J, K (L, M, R) | water | water | 18.0 | 104 | Chemie (HOH) |
Sequence modifications
L, M: 1 - 106 (UniProt: P48607)
R: 28 - 397 (UniProt: P08953)
R: 400 - 468 (UniProt: Q4G1L2)
| PDB | External Database | Details |
|---|---|---|
| Gly 0 | - | expression tag |
| PDB | External Database | Details |
|---|---|---|
| Ala 398 | - | linker |
| Ser 399 | - | linker |
| Gly 469 | - | expression tag |
| Glu 470 | - | expression tag |
| Asn 471 | - | expression tag |
| Leu 472 | - | expression tag |
| Tyr 473 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 74735.0 | |
| Branched | Number of molecules | 1 |
| Total formula weight | 1397.2 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 884.8 | |
| All* | Total formula weight | 77017.0 |
