4BUP
A novel route to product specificity in the Suv4-20 family of histone H4K20 methyltransferases
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 | polymer | 271 | 31231.4 | 2 | UniProt (Q3U8K7) Pfam (PF00856) | MUS MUSCULUS (HOUSE MOUSE) | SUPPRESSOR OF VARIEGATION 4-20 HOMOLOG 1, SU(VAR)4-20 HOMOLOG 1, SUV4-20H1 |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G (A, B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) PubChem (5136) PubChem (34755) PubChem (58633578) PubChem (60038769) PubChem (73897310) PubChem (58766358) PubChem (87224684) PubChem (131697735) PubChem (9865603) PubChem (145712080) PubChem (12312798) PubChem (132988922) PubChem (134692588) PubChem (135030730) PubChem (140459785) PubChem (163046094) | |||
| 4 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) PubChem (753) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 198 | Chemie (HOH) |
Sequence modifications
A, B: 61 - 327 (UniProt: Q3U8K7)
| PDB | External Database | Details |
|---|---|---|
| Gly 57 | - | expression tag |
| Ser 58 | - | expression tag |
| His 59 | - | expression tag |
| Met 60 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62462.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1019.8 | |
| All* | Total formula weight | 63482.6 |
