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4BUP

A novel route to product specificity in the Suv4-20 family of histone H4K20 methyltransferases

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1polymer27131231.42UniProt (Q3U8K7)
Pfam (PF00856)
MUS MUSCULUS (HOUSE MOUSE)SUPPRESSOR OF VARIEGATION 4-20 HOMOLOG 1, SU(VAR)4-20 HOMOLOG 1, SUV4-20H1
2C, F
(A, B)
ZINC IONnon-polymer65.42Chemie (ZN)
3D, G
(A, B)
S-ADENOSYLMETHIONINEnon-polymer398.42Chemie (SAM)
4E
(A)
GLYCEROLnon-polymer92.11Chemie (GOL)
5H, I
(A, B)
waterwater18.0198Chemie (HOH)
Sequence modifications
A, B: 61 - 327 (UniProt: Q3U8K7)
PDBExternal DatabaseDetails
Gly 57-expression tag
Ser 58-expression tag
His 59-expression tag
Met 60-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight62462.8
Non-Polymers*Number of molecules5
Total formula weight1019.8
All*Total formula weight63482.6
*Water molecules are not included.

247536

PDB entries from 2026-01-14

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