4BUP
A novel route to product specificity in the Suv4-20 family of histone H4K20 methyltransferases
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H1 | polymer | 271 | 31231.4 | 2 | UniProt (Q3U8K7) Pfam (PF00856) | MUS MUSCULUS (HOUSE MOUSE) | SUPPRESSOR OF VARIEGATION 4-20 HOMOLOG 1, SU(VAR)4-20 HOMOLOG 1, SUV4-20H1 |
| 2 | C, F (A, B) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 3 | D, G (A, B) | S-ADENOSYLMETHIONINE | non-polymer | 398.4 | 2 | Chemie (SAM) | |||
| 4 | E (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | H, I (A, B) | water | water | 18.0 | 198 | Chemie (HOH) |
Sequence modifications
A, B: 61 - 327 (UniProt: Q3U8K7)
| PDB | External Database | Details |
|---|---|---|
| Gly 57 | - | expression tag |
| Ser 58 | - | expression tag |
| His 59 | - | expression tag |
| Met 60 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 62462.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 1019.8 | |
| All* | Total formula weight | 63482.6 |






