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4BTT

factor Xa in complex with the dual thrombin-FXa inhibitor 31.

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, C
(A, E)
COAGULATION FACTOR X LIGHT CHAINpolymer9610533.72UniProt (P00742)
Pfam (PF00008)
Pfam (PF14670)
HOMO SAPIENS (HUMAN)STUART FACTOR, STUART-PROWER FACTOR, FACTOR X LIGHT CHAIN
2B, D
(B, F)
COAGULATION FACTOR Xpolymer25428550.62UniProt (P00742)
Pfam (PF00089)
HOMO SAPIENS (HUMAN)STUART FACTOR, STUART-PROWER FACTOR, FACTOR X HEAVY CHAIN
3E, G
(B, F)
CALCIUM IONnon-polymer40.12Chemie (CA)
4F, H
(B, F)
N-[(S)-1-[5-(5-Chloro-thiophen-2-yl)-isoxazol-3-ylmethyl]-2-(4-methoxy-piperidin-1-yl)-2-oxo-ethyl]-2-ethyl-3-(3-oxo-morpholin-4-yl)-benzenesulfonamidenon-polymer637.22Chemie (VYR)
5I, J, K, L
(A, B, E, F)
waterwater18.0224Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight78168.6
Non-Polymers*Number of molecules4
Total formula weight1354.5
All*Total formula weight79523.1
*Water molecules are not included.

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PDB entries from 2025-06-11

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