Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005509 | molecular_function | calcium ion binding |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| E | 0005509 | molecular_function | calcium ion binding |
| F | 0004252 | molecular_function | serine-type endopeptidase activity |
| F | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA B 1245 |
| Chain | Residue |
| B | ASP70 |
| B | ASN72 |
| B | GLN75 |
| B | GLU77 |
| B | GLU80 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA F 1245 |
| Chain | Residue |
| F | HOH2022 |
| F | ASP70 |
| F | ASN72 |
| F | GLN75 |
| F | GLU80 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE VYR B 1246 |
| Chain | Residue |
| B | HIS57 |
| B | GLN61 |
| B | THR98 |
| B | TYR99 |
| B | PHE174 |
| B | ALA190 |
| B | CYS191 |
| B | GLN192 |
| B | VAL213 |
| B | SER214 |
| B | TRP215 |
| B | GLY216 |
| B | GLY226 |
| B | TYR228 |
| B | HOH2082 |
| F | ASN92 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE VYR F 1246 |
| Chain | Residue |
| F | GLN61 |
| F | GLU97 |
| F | THR98 |
| F | TYR99 |
| F | PHE174 |
| F | ALA190 |
| F | CYS191 |
| F | GLN192 |
| F | VAL213 |
| F | SER214 |
| F | TRP215 |
| F | GLY216 |
| F | GLY226 |
| F | TYR228 |
| F | HOH2074 |
Functional Information from PROSITE/UniProt
| site_id | PS00010 |
| Number of Residues | 12 |
| Details | ASX_HYDROXYL Aspartic acid and asparagine hydroxylation site. CkDglgeYtCtC |
| Chain | Residue | Details |
| A | CYS-24-CYS-13 | |
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. CtCleGfeGKnC |
| Chain | Residue | Details |
| A | CYS-15-CYS-4 | |
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. LTAAHC |
| Chain | Residue | Details |
| B | LEU53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DAcqGDSGGPHV |
| Chain | Residue | Details |
| B | ASP189-VAL200 | |
| site_id | PS01186 |
| Number of Residues | 12 |
| Details | EGF_2 EGF-like domain signature 2. CtCleGFegkn....C |
| Chain | Residue | Details |
| A | CYS-15-CYS-4 | |
| A | CYS21-CYS36 | |
| site_id | PS01187 |
| Number of Residues | 25 |
| Details | EGF_CA Calcium-binding EGF-like domain signature. DgDQCetsp..........Cqnqgk..CkDglgeYtC |
| Chain | Residue | Details |
| A | ASP-39-CYS-15 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 464 |
| Details | Domain: {"description":"Peptidase S1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00274","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Charge relay system"} |
