4BTK
TTBK1 in complex with inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | TAU-TUBULIN KINASE 1 | polymer | 337 | 38746.5 | 1 | UniProt (Q5TCY1) Pfam (PF00069) | HOMO SAPIENS (HUMAN) | BRAIN-DERIVED TAU KINASE |
| 2 | B (A) | DIMETHYL SULFOXIDE | non-polymer | 78.1 | 1 | Chemie (DMS) | |||
| 3 | C (A) | 4-[3-HYDROXYANILINO]-6,7-DIMETHOXYQUINAZOLINE | non-polymer | 297.3 | 1 | Chemie (DTQ) | |||
| 4 | D (A) | water | water | 18.0 | 181 | Chemie (HOH) |
Sequence modifications
A: 25 - 337 (UniProt: Q5TCY1)
| PDB | External Database | Details |
|---|---|---|
| Met 1 | - | expression tag |
| His 2 | - | expression tag |
| His 3 | - | expression tag |
| His 4 | - | expression tag |
| His 5 | - | expression tag |
| His 6 | - | expression tag |
| His 7 | - | expression tag |
| Ser 8 | - | expression tag |
| Ser 9 | - | expression tag |
| Gly 10 | - | expression tag |
| Val 11 | - | expression tag |
| Asp 12 | - | expression tag |
| Leu 13 | - | expression tag |
| Gly 14 | - | expression tag |
| Thr 15 | - | expression tag |
| Glu 16 | - | expression tag |
| Asn 17 | - | expression tag |
| Leu 18 | - | expression tag |
| Tyr 19 | - | expression tag |
| Phe 20 | - | expression tag |
| Gln 21 | - | expression tag |
| Ser 22 | - | expression tag |
| Asn 23 | - | expression tag |
| Ala 24 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 38746.5 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 375.4 | |
| All* | Total formula weight | 39122.0 |
