4BTH
The LeuA146Trp,PheB24Tyr Double Mutant of the Quorum Quenching N-acyl Homoserine Lactone Acylase PvdQ Has an Altered Substrate Specificity Towards Small Acyl Chains
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | ACYL-HOMOSERINE LACTONE ACYLASE PVDQ SUBUNIT ALPHA | polymer | 170 | 18666.0 | 1 | UniProt (Q9I194) In PDB | PSEUDOMONAS AERUGINOSA | AHL ACYLASE PVDQ, ACYL-HSL ACYLASE PVDQ, ACYL-HSL ACYLASE PVDQ SUBUNIT ALPHA, |
2 | B | ACYL-HOMOSERINE LACTONE ACYLASE PVDQ SUBUNIT BETA | polymer | 546 | 60505.9 | 1 | UniProt (Q9I194) Pfam (PF01804) In PDB | PSEUDOMONAS AERUGINOSA | AHL ACYLASE PVDQ, ACYL-HSL ACYLASE PVDQ, ACYL-HSL ACYLASE PVDQ SUBUNIT BETA |
3 | A, B | GLYCEROL | non-polymer | 92.1 | 5 | Chemie (GOL) | |||
4 | water | water | 18.0 | 254 | Chemie (HOH) |
Sequence modifications
A: 1 - 170 (UniProt: Q9I194)
B: 1 - 546 (UniProt: Q9I194)
PDB | External Database | Details |
---|---|---|
Trp 146 | Leu 169 | engineered mutation |
PDB | External Database | Details |
---|---|---|
Tyr 24 | Phe 240 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 79171.9 | |
Non-Polymers* | Number of molecules | 5 |
Total formula weight | 460.5 | |
All* | Total formula weight | 79632.4 |