4BSW
Heterodimeric Fc Antibody Azymetric Variant 2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | HETERODIMERIC FC ANTIBODY AZYMETRIC VARIANT 2 | polymer | 226 | 25301.6 | 1 | UniProt (P01857) Pfam (PF07654) In PDB | HOMO SAPIENS (HUMAN) | |
2 | B | HETERODIMERIC FC ANTIBODY AZYMETRIC VARIANT 2 | polymer | 226 | 25472.9 | 1 | UniProt (P01857) Pfam (PF07654) In PDB | HOMO SAPIENS (HUMAN) | |
3 | C, D | beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | branched | 1625.5 | 2 | In PDB GlyTouCan (G27919IH) | |||
4 | A, B | 1,2-ETHANEDIOL | non-polymer | 62.1 | 5 | Chemie (EDO) | |||
5 | A, B | IODIDE ION | non-polymer | 126.9 | 3 | Chemie (IOD) | |||
6 | water | water | 18.0 | 371 | Chemie (HOH) |
Sequence modifications
A: 223 - 447 (UniProt: P01857)
B: 223 - 447 (UniProt: P01857)
PDB | External Database | Details |
---|---|---|
Gly 222 | - | expression tag |
Val 350 | Thr 233 | engineered mutation |
Tyr 351 | Leu 234 | microheterogeneity |
Leu 366 | Thr 249 | microheterogeneity |
Leu 392 | Lys 275 | microheterogeneity |
Thr 394 | Trp 277 | microheterogeneity |
Ala 405 | Phe 288 | microheterogeneity |
Val 407 | Tyr 290 | microheterogeneity |
PDB | External Database | Details |
---|---|---|
Gly 222 | - | expression tag |
Val 350 | Thr 233 | engineered mutation |
Tyr 351 | Leu 234 | microheterogeneity |
Leu 366 | Thr 249 | microheterogeneity |
Leu 392 | Lys 275 | microheterogeneity |
Thr 394 | Trp 277 | microheterogeneity |
Ala 405 | Phe 288 | microheterogeneity |
Val 407 | Tyr 290 | microheterogeneity |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 50774.5 | |
Branched | Number of molecules | 2 |
Total formula weight | 3251.0 | |
Non-Polymers* | Number of molecules | 8 |
Total formula weight | 691.1 | |
All* | Total formula weight | 54716.6 |