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4BRX

Focal Adhesion Kinase catalytic domain in complex with a diarylamino- 1,3,5-triazine inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
FOCAL ADHESION KINASE 1polymer27631731.81UniProt (Q00944)
Pfam (PF07714)
GALLUS GALLUS (CHICKEN)FADK 1, FOCAL ADHESION KINASE-RELATED NONKINASE, FRNK, P41/P43FRNK, PROTEIN-TYROSINE KINASE 2, P125FAK, PP125FAK
2B
(A)
2-(4-(2-methoxy-4-morpholinophenylamino)-1,3,5-triazin-2-ylamino)-N-methylbenzamidenon-polymer435.51Chemie (KGW)
3C
(A)
SULFATE IONnon-polymer96.11Chemie (SO4)
4D
(A)
waterwater18.045Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight31731.8
Non-Polymers*Number of molecules2
Total formula weight531.5
All*Total formula weight32263.3
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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