4BQM

Crystal structure of human liver-type glutaminase, catalytic domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	GLUTAMINASE LIVER ISOFORM, MITOCHONDRIAL	polymer	349	38473.0	2	UniProt (Q9UI32) Pfam (PF04960)	HOMO SAPIENS (HUMAN)	GLS, L-GLUTAMINASE, L-GLUTAMINE AMIDOHYDROLASE, HUMAN LIVER-TYPE GLUTAMINASE
2	C, D, E, G, H (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	5	Chemie (EDO)
3	F, I (A, B)	CHLORIDE ION	non-polymer		35.5	2	Chemie (CL)
4	J, K (A, B)	water	water		18.0	168	Chemie (HOH)

Sequence modifications

A, B: 154 - 479 (UniProt: Q9UI32)

PDB	External Database	Details
Met -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
Ser -15	-	expression tag
Ser -14	-	expression tag
Gly -13	-	expression tag
Val -12	-	expression tag
Asp -11	-	expression tag
Leu -10	-	expression tag
Gly -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Ser -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	76946.1
Non-Polymers*	Number of molecules	7
	Total formula weight	381.2
All*	Total formula weight	77327.3

*Water molecules are not included.