4BQ7

Crystal structure of the RGMB-Neo1 complex form 2

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	NEOGENIN	polymer	264	29221.8	2	UniProt (P97798) Pfam (PF00041) In PDB	MUS MUSCULUS (HOUSE MOUSE)
2	C, E	RGM DOMAIN FAMILY MEMBER B	polymer	122	13318.7	2	UniProt (Q6NW40) Pfam (PF06535) In PDB	HOMO SAPIENS (HUMAN)	DRG11-RESPONSIVE AXONAL GUIDANCE AND OUTGROWTH OF NEURITE, DRAGON
3	D, F	RGM DOMAIN FAMILY MEMBER B	polymer	251	27945.4	2	UniProt (Q6NW40) Pfam (PF06535) Pfam (PF06534) In PDB	HOMO SAPIENS (HUMAN)	DRG11-RESPONSIVE AXONAL GUIDANCE AND OUTGROWTH OF NEURITE,

Sequence modifications

A, B: 883 - 1133 (UniProt: P97798)

PDB	External Database	Details
Glu 880	-	expression tag
Thr 881	-	expression tag
Gly 882	-	expression tag
Asn 1134	-	expression tag
Gly 1135	-	expression tag
Thr 1136	-	expression tag
Lys 1137	-	expression tag
His 1138	-	expression tag
His 1139	-	expression tag
His 1140	-	expression tag
His 1141	-	expression tag
His 1142	-	expression tag
His 1143	-	expression tag

C, E: 50 - 168 (UniProt: Q6NW40)

PDB	External Database	Details
Glu 47	-	expression tag
Thr 48	-	expression tag
Gly 49	-	expression tag

D, F: 169 - 410 (UniProt: Q6NW40)

PDB	External Database	Details
Gly 411	-	expression tag
Thr 412	-	expression tag
Lys 413	-	expression tag
His 414	-	expression tag
His 415	-	expression tag
His 416	-	expression tag
His 417	-	expression tag
His 418	-	expression tag
His 419	-	expression tag
Gly 225	Glu 225	conflict

Contents of the asymmetric unit

Polymers	Number of chains	6
	Total formula weight	140971.8
All*	Total formula weight	140971.8

*Water molecules are not included.