4BO4

Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (FabG) from Pseudomonas aeruginosa in complex with N-(2-methoxyphenyl)-3,4- dihydro-2H-quinoline-1-carboxamide at 2.7A resolution

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	3-OXOACYL-[ACYL-CARRIER-PROTEIN] REDUCTASE FABG	polymer	269	28168.0	4	UniProt (O54438) Pfam (PF13561)	PSEUDOMONAS AERUGINOSA	3-OXOACYL-ACYL-CARRIER-PROTEIN REDUCTASE, 3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE, BETA-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE, BETA-KETOACYL-ACP REDUCTASE, 3-OXOACYL-ACP REDUCTASE
2	E, F (A, C)	N-(2-methoxyphenyl)-3,4-dihydro-2H-quinoline-1-carboxamide	non-polymer		282.3	2	Chemie (36G)
3	G, H, I, J (A, B, C, D)	water	water		18.0	30	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 247 (UniProt: O54438)

PDB	External Database	Details
Met -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Val -11	-	expression tag
Asp -10	-	expression tag
Leu -9	-	expression tag
Gly -8	-	expression tag
Thr -7	-	expression tag
Glu -6	-	expression tag
Asn -5	-	expression tag
Leu -4	-	expression tag
Tyr -3	-	expression tag
Phe -2	-	expression tag
Gln -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	112671.8
Non-Polymers*	Number of molecules	2
	Total formula weight	564.7
All*	Total formula weight	113236.5

*Water molecules are not included.